Vasopressor SAT Study
| Status: | Recruiting |
|---|---|
| Conditions: | Cardiology, Hospital, Neurology, Psychiatric |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Neurology, Psychiatry / Psychology, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 7/14/2018 |
| Start Date: | July 1, 2017 |
| End Date: | May 2019 |
| Contact: | John P Kress, MD |
| Email: | jkress@medicine.bsd.uchicago.edu |
| Phone: | 773-702-6404 |
An Assessment of Vasoactive Medication Dose in Mechanically Ventilated Patients Undergoing Daily Sedation Awakening Trial (SAT)
To assess the impact of daily awakening from sedation on the amount of vasoactive medication
required in the ICU. The hypothesis of this proposal is that the amount of vasoactive drug
required to maintain an adequate mean arterial blood pressure will be reduced during a daily
awakening from sedation.
required in the ICU. The hypothesis of this proposal is that the amount of vasoactive drug
required to maintain an adequate mean arterial blood pressure will be reduced during a daily
awakening from sedation.
This observational study will compare mean arterial pressure and vasoactive drug dose
recorded at two time points:
1. prior to awakening from sedation
2. during the awakening from sedation trial The vasoactive infusion will be titrated to a
mean arterial pressure as determined by the medical team prior to study enrollment. Each
enrolled patient will have measurements taken only on the first day of enrollment.
Enrolled subjects will also have a delirium assessment using the CAM-ICU tool before the
awakening from sedation trial and during the awakening from sedation trial.
recorded at two time points:
1. prior to awakening from sedation
2. during the awakening from sedation trial The vasoactive infusion will be titrated to a
mean arterial pressure as determined by the medical team prior to study enrollment. Each
enrolled patient will have measurements taken only on the first day of enrollment.
Enrolled subjects will also have a delirium assessment using the CAM-ICU tool before the
awakening from sedation trial and during the awakening from sedation trial.
Inclusion Criteria:
- requiring Mechanical ventilation through an endotracheal tube with infusion of
sedative or analgesic agent for comfort
- requiring vasoactive drug via central venous catheter for the treatment of shock
Exclusion Criteria:
- patients receiving Dexmedetomidine as sedative
We found this trial at
1
site
5841 S Maryland Ave
Chicago, Illinois 60637
Chicago, Illinois 60637
(773) 702-1000
Phone: 773-702-6404
University of Chicago Medical Center The University of Chicago Medicine has been at the forefront...
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