Hematopoetic Stem Cell Transplant and Physical Function

The researchers will quantify the decline in physical function of HSCT patients using valid
and reliable tests aimed to mimic activities of daily living, quantify cardiovascular health,
and quantify muscle power declines. Also, patients will undergo a walking program during
their hospitalization, which is designed to increase physical activity levels and maintain
and improve physical function and quality of life. Additionally, using valid and reliable
questionnaires, the researchers will gauge perception of exercise, quantify current exercise
levels, determine preference of exercise programs and counseling, and measure differences in
quality of life before and after HSCT treatment.

Inclusion Criteria:

- Be between 40 and 80 years of age

- Willing and able to provide written informed consent in English

- Ability to comprehend the purpose of the study

- Be scheduled to receive an autologous or allogeneic hematopoietic stem cell transplant
at Sylvester Comprehensive Cancer Center

- Have an expected hospital stay of at least 2 weeks

- Not currently be participating in an exercise training program

Exclusion Criteria:

- Dementia, altered mental status, or psychiatric condition

- Received erythropoiesis-stimulating proteins within 4 weeks prior to enrollment

- Comorbid conditions that would contraindicate exercise testing

- Undergoing concurrent non-transplant-related chemotherapy or radiation