The Effect of Manipulation of the Cervical Spine on Pain Biomarkers
| Status: | Completed |
|---|---|
| Conditions: | Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 20 - 45 |
| Updated: | 6/15/2017 |
| Start Date: | August 15, 2016 |
| End Date: | September 20, 2016 |
The Effect of High-Velocity Low-Amplitude Thrust Manipulation of the Cervical Spine on Pain Biomarkers in Females With Non-Specific Mechanical Neck Pain
This study evaluates the effect of high-velocity low-amplitude thrust (HVLAT) manipulation
to the cervical spine on neuropeptide expression as determined by the plasma concentration
of oxytocin, neurotensin, orexin A and cortisol; and Examine the effect of HVLAT
manipulation on pain perception in symptomatic females with non-specific mechanical cervical
spine pain
to the cervical spine on neuropeptide expression as determined by the plasma concentration
of oxytocin, neurotensin, orexin A and cortisol; and Examine the effect of HVLAT
manipulation on pain perception in symptomatic females with non-specific mechanical cervical
spine pain
A high-velocity low-amplitude thrust (HVLAT) manipulation or commonly known as a spinal
manipulation, is an intervention frequently used by physical therapists and other healthcare
practitioners as an alternative treatment to help relieve spinal pain The mechanism by which
HVLAT manipulation modulates pain remains undefined, although this does not contradict the
clinical effects from HVLAT manipulation. Furthermore, there is evidence that suggests
analgesia after HVLAT manipulation. There is a variety of observed and proposed phenomena
that can explain the mechanisms for the psychological, mechanical, or neurophysiological
responses from a HVLAT manipulation associated with alterations in pain processing or
sympathetic and motor systems' excitation.
manipulation, is an intervention frequently used by physical therapists and other healthcare
practitioners as an alternative treatment to help relieve spinal pain The mechanism by which
HVLAT manipulation modulates pain remains undefined, although this does not contradict the
clinical effects from HVLAT manipulation. Furthermore, there is evidence that suggests
analgesia after HVLAT manipulation. There is a variety of observed and proposed phenomena
that can explain the mechanisms for the psychological, mechanical, or neurophysiological
responses from a HVLAT manipulation associated with alterations in pain processing or
sympathetic and motor systems' excitation.
Inclusion Criteria:
- 20 - 45 years of age
- A score of 10 or more out of 50 on the Neck Disability Index (NDI) questionnaire
- Symptoms of pain present for 30 days or less and no pain symptoms below your shoulder
Exclusion Criteria:
- Serious condition (such as cancer, spondylolisthesis, rheumatoid arthritis, or
ankylosing spondylitis)
- Cervical spinal stenosis signs (such as incoordination in hands, arms and legs,
inability of walking at a brisk pace, or bowel and bladder incontinence)
- Nerve root compression (such as changes in sensation, muscle weakness, or decreased
reflexes)
- Works the night shift
- Steroid medication within 3 months
- Pregnancy or postpartum
- Pending legal action regarding their neck pain
- History of whiplash associated disorder and/or cervical spine surgery
We found this trial at
1
site
Loma Linda University Loma Linda University (LLU) is a Seventh-day Adventist educational health-sciences institution with...
Click here to add this to my saved trials
