Celecoxib Treatment for Lung Cancer
| Status: | Archived |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
Celecoxib-Mediated Inhibition of T Regulatory Cells in Human Lung Cancer
This proposal evaluates cyclooxygenase 2 (COX-2) inhibition as a means to decrease T
regulatory cell activities and thus augment immune responses against lung cancer. The broad
goal focuses on understanding how COX-2 expression regulates the malignant phenotype in non
small cell lung cancer in an effort to foster an informed approach for the use of COX-2
inhibitors in prevention and therapy for lung cancer.
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