Neuroprognostication Using Optic Nerve Sheath Diameter

This study involves patients who have experienced either an in-hospital or out-of-hospital
cardiopulmonary arrest, and who meet the 2015 American Heart Association (AHA)
inclusion/exclusion criteria for targeted temperature management [i.e., they are comatose or
exhibit no meaningful response to verbal commands with return of spontaneous circulation
(ROSC) after cardiac arrest]. After induction of hypothermia protocol after cardiopulmonary
arrest (i.e., targeted temperature management), patients will undergo ocular ultrasound at
three time points.

Inclusion Criteria:

- Patient ≥ 18 years of age

- Patient has experienced either an in-hospital or out-of-hospital cardiopulmonary
arrest

- Patient is comatose or exhibits lack of meaningful response to verbal commands with
return of spontaneous circulation (ROSC) after cardiopulmonary arrest

- Patient must meet all inclusion criteria as deemed by physician and the 2015 American
Heart Association standards for targeted temperature management (TTM) following
cardiopulmonary arrest

Exclusion Criteria:

- Patient < 18 years of age

- Patient does not meet inclusion criteria for targeted temperature management (TTM)

- Unable to obtain consent from Legal Authorized Representative (LAR)

- Patient has a Do Not Resuscitate (DNR) order or a Do Not Intubate (DNI) order at the
time of consent

- Patient has uncontrollable bleeding

- Patient is able to follow verbal commands

- Patient has another medical condition creating increased ocular pressure, as deemed by
physician