A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease
| Status: | Completed |
|---|---|
| Conditions: | Parkinsons Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 7/20/2017 |
| Start Date: | December 2011 |
| End Date: | June 2013 |
The primary objective of this study is to investigate the effects of a theoretically driven,
highly challenging exercise program (balance and strengthening exercises) in reducing fall
rate, improving balance and reducing fear of falling in persons with Parkinson's disease.
In this pilot, randomized, cross-over study, 32 participants with Parkinson disease will be
randomly assigned to either an early start (immediately following enrollment) or late start
(3 months after enrollment) multifactorial exercise program which will meet 2 times per week
for 1.5 hours over 3 months. The exercise program will consist of balance and strengthening
exercises which will be individualized depending on the ability of each participant. Fall
rate, balance, walking ability, fear of falling, mood, anxiety, and quality of life will be
measured prior to the start, at 3 months and 6 months after enrollment. Subjects will be
enrolled for 6-7 months.
highly challenging exercise program (balance and strengthening exercises) in reducing fall
rate, improving balance and reducing fear of falling in persons with Parkinson's disease.
In this pilot, randomized, cross-over study, 32 participants with Parkinson disease will be
randomly assigned to either an early start (immediately following enrollment) or late start
(3 months after enrollment) multifactorial exercise program which will meet 2 times per week
for 1.5 hours over 3 months. The exercise program will consist of balance and strengthening
exercises which will be individualized depending on the ability of each participant. Fall
rate, balance, walking ability, fear of falling, mood, anxiety, and quality of life will be
measured prior to the start, at 3 months and 6 months after enrollment. Subjects will be
enrolled for 6-7 months.
Inclusion Criteria:
- have a diagnosis of idiopathic Parkinson's disease (using UK Brain Bank Criteria)
- have a Hoehn & Yahr stage of 2-4 during the "ON" state
- Mini mental status score > 26
- be 40 years of age or older, so as to represent the typical age range of PD
- be on a stable dose of Parkinson's medications for at least 2 weeks prior to study
onset and during the 3 month study period.
- have experienced at least one fall in the past 3 months and greater or equal to 2
falls in the past one-year (A fall was defined as an unexpected event where the person
inadvertently came to rest on the ground or other lower level not due to a major
intrinsic or extrinsic event)
- able to walk without physical assistance or an assistive device for at least 5
continuous minutes
- able to understand, communicate with and be understood by recruitment personnel
- able to attend the exercise program twice per week at Sargent College
- be interested in participating and provide informed consent
Exclusion Criteria:
- have a diagnosis of atypical Parkinsonism
- have a Hoehn & Yahr stage of 1 or 5
- have had previous surgical management of PD (i.e., deep brain stimulation surgery;
pallidotomy)
- serious co-morbidities that may interfere with ability to participate in an exercise
program (i.e., musculoskeletal, cardiovascular, and neurological (other than
Parkinson's))
- be pregnant
We found this trial at
1
site
Boston, Massachusetts 02215
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