FFRangio Accuracy vs. Standard FFR

Inclusion Criteria:

- Male or female subjects, >18 years of age.

- Patients with stable angina or unstable angina or NSTEMI, and in whom invasive FFR is
being assessed in a non-culprit stenosis in at least one coronary artery.

- Subject is undergoing invasive FFR with Adenosine, ATP or Papaverine used as hyperemic
stimulus.

- Provides written, informed consent (where required)

Exclusion Criteria:

- Contraindication for FFR examination or administration of vasodilators.

- Subject is presenting with acute infarct (STEMI) OR has documented prior STEMI on same
side (right/left).

- CTO in target vessel.

- Prior CABG, heart transplant or valve surgery, or prior TAVI/TAVR.

- Known LVEF ≤45%.

- Arteries supplying akinetic or severe hypokinetic territories if already known based
on prior imaging.

- TIMI Grade 2 or lower at baseline.

- Target lesion involves Left Main (stenosis >50%).

- PCI with stent in target vessel in past 12 months, or target vessel involves in-stent
restenosis.

- Severe, diffuse disease defined as the presence of diffuse, serial gross luminal
irregularities present in the majority of the coronary tree.

- Target coronary vessel is supplied by major collaterals.