A Study Comparing Tazarotene Cream 0.05% to TAZORAC® (Tazarotene) Cream 0.05% and Both to a Placebo Control in the Treatment of Plaque Psoriasis



Status:Completed
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:8/31/2018
Start Date:September 19, 2016
End Date:August 2, 2017

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A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing Tazarotene Cream 0.05% to TAZORAC® (Tazarotene) Cream 0.05% and Both Active Treatments to a Vehicle Control in the Treatment of Stable Plaque Psoriasis

A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing
Tazarotene Cream 0.05% to TAZORAC® (tazarotene) Cream 0.05% and Both Active Treatments to a
Vehicle Control in the Treatment of Stable Plaque Psoriasis


Inclusion Criteria:

- Have a definite clinical diagnosis of stable (at least 6 months) plaque psoriasis,
involving at least 2% and no more than 20% of the body surface area (BSA) (not
including the scalp and intertriginous areas)

- Have a minimum plaque elevation at the target lesion site of at least moderate
severity (grade ≥ 3 on the Psoriasis Area Severity Index [PASI]). The most severe
lesion at baseline should be identified as the target lesion

- Have an Investigator's Global Assessment (IGA) of disease severity of at least
moderate (score ≥ 3) as an overall assessment of all lesions to be treated.

Exclusion Criteria:

- A female subject who is pregnant, nursing, planning a pregnancy, or does not agree to
use an acceptable form of birth control within the study participation period

- Have a current diagnosis of unstable forms of psoriasis in the treatment area,
including pustular, guttate, exfoliative or erythrodermic psoriasis

- Have a history of psoriasis unresponsive to topical treatments
We found this trial at
28
sites
Phoenix, Arizona 85018
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Anaheim, California 92801
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Arlington Heights, Illinois 60005
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Arlington Heights, IL
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Brandon, Florida 33511
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Brandon, FL
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Coral Gables, Florida 33134
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Coral Gables, FL
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Hazleton, Pennsylvania 18201
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Hazleton, PA
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Henderson, Nevada 89052
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Henderson, NV
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Hialeah, Florida 33016
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Hialeah, FL
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High Point, North Carolina 27262
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High Point, NC
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Hot Springs, Arkansas 71913
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Hot Springs, AR
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Lake Charles, Louisiana 70605
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Lake Charles, LA
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Louisville, Kentucky 40202
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Louisville, KY
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Macon, Georgia 31217
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Macon, GA
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Miami, Florida 33015
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Miami, FL
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Miami Gardens, Florida 33169
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Miami Gardens, FL
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Miramar, Florida 33027
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Miramar, FL
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New Albany, Indiana 47150
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New Albany, IN
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North Hollywood, California 91606
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North Hollywood, CA
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Plainfield, Indiana 46168
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Plainfield, IN
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Saint Joseph, Missouri 91606
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Saint Joseph, MO
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Salem, Oregon 97302
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Salem, OR
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San Antonio, Texas 78207
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San Antonio, TX
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San Diego, California 92108
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San Diego, CA
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San Ramon, California 94582
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San Ramon, CA
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Sweetwater, Florida 33172
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Sweetwater, FL
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Tampa, Florida 33618
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Tampa, FL
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Upper Saint Clair, Pennsylvania 15241
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Upper Saint Clair, PA
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West Palm Beach, Florida 33406
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West Palm Beach, FL
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