Dietary Intake in Adults From the GA2LEN Folow-up Survey



Status:Completed
Conditions:Allergy, Asthma, Asthma, Chronic Obstructive Pulmonary Disease, Food Studies, Neurology
Therapuetic Areas:Neurology, Otolaryngology, Pharmacology / Toxicology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:15 - 75
Updated:8/17/2017
Start Date:January 1, 2007
End Date:December 31, 2010

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Dietary Intake, Allergy and Respiratory Diseases in European Adults From the GA2LEN Follow-up Survey

The Nutrition Study of the GA2LEN Follow-Survey was designed to investigate the association
between usual dietary intake and allergic and respiratory outcomes in adults across Europe.
Within this framework, a food frequency questionnaire (FFQ) was designed to ascertain usual
dietary intake of 250 food items, which was translated into the languages of the participant
centres. Information on daily intake of foods, nutrients, and flavonoids was derived.

Within the GA2LEN Follow-up Survey, the Nutrition study was aimed at assessing dietary intake
in adults across European countries and its association with various outcomes of allergy and
respiratory health. In absence of an internationally comparable dietary questionnaire to
ascertain usual dietary intake, a single and standardized food frequency questionnaire (FFQ)
was design to be used as a common instrument in all participant countries. The FFQ is
comprised of 32 food sections and 250 food items. The FFQ sections were designed following
the recommendations by the EFCOSUM Group, which facilitate international comparisons of
dietary intake. It also included several staple foods to capture locally representative
dietary intake.

Participants reported how often they had consumed each of the foods over the previous month,
using eight predefined options (rarely or never, 1-3 times per month, once, 2-4, or 5-6 times
per week, once, 2-3 times per day). Standard food portion sizes were used to quantify the
intake following the recommendations from the UK's Food Standards Agency. Daily intake of
foods (g) were estimated and macro- and micronutrient and flavonoid intakes were derived. The
GA2LEN FFQ was validated in five EU countries, namely Finland, UK, Portugal, Germany, Poland,
and Greece, and demonstrated to be a good tool to assess mid-term intake of foods,
specifically essential polyunsaturated fatty acids (PUFAs). The instrument has also been
demonstrated to be an accurate tool to assess dietary sources of flavonoids.

Various approaches were planned to derive dietary exposures and to examine their association
with respiratory and allergic outcomes. These included the use of dietary patterns derived
from Principal Component Analysis (PCA), a dietary inflammatory index (DII), as well as
single antioxidants, and individual food items.

Inclusion Criteria:

Participants aged 15-75 years old, who had responded to the GA2LEN Baseline survey and who
met the definition of cases or controls (as described below)

Exclusion Criteria:

Participants who had not completed the baseline survey
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