The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances

Inclusion Criteria:

- Presence of permanent dentition

- Eligible and scheduled for full-mouth, fixed-appliance orthodontic treatment

- Moderate to severe crowding (LII ≥ 3 mm), with no labio-lingually displaced teeth

- Class I or Class II malocclusion by ½ cusp or less

- Non-extraction in both arches

- Age 11-60

- Good oral hygiene

- Non-smoker; non-use of chewing tobacco

Exclusion Criteria:

- Subject is currently enrolled in another clinical study

- Subject decided on Invisalign rather than braces

- Periodontally involved teeth

- Use of bisphosphonates (osteoporosis drugs) during the study

- Subject plans to relocate over the treatment period

- Spaces between anterior teeth

- Subject has dental implants or an implanted prosthesis

- Sponsor employees, the Investigator and staff, as well as their immediate family
members