A Randomized, Double-blind Study of the Effects of Fenretinide Administered in Subjects With Obesity



Status:Completed
Conditions:Obesity Weight Loss, Endocrine
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 65
Updated:4/2/2016
Start Date:December 2007
End Date:April 2015
Contact:Monique Gagnon, B.A.
Email:monique.gagnon@va.gov
Phone:858-552-8585

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Phase 2 Study of the Assessment of the Insulin Sensitizing Activity of Fenretinide in Subjects With Insulin Resistance With BMI >30Kg/m2, and Liver Inflammation Related to Non-alcoholic Fatty Liver

Many metabolic complications of obesity are a consequence of abnormal responses of the
liver, muscle, and fat to insulin actions. Fenretinide may improve the effects of insulin,
preventing metabolic complications.


Inclusion Criteria:

- BMI >30

Exclusion Criteria:

- Diabetes Requiring Medication

- Poorly Controlled Co-Morbidities
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