A Randomized, Double-blind Study of the Effects of Fenretinide Administered in Subjects With Obesity
Status: | Completed |
---|---|
Conditions: | Obesity Weight Loss, Endocrine |
Therapuetic Areas: | Endocrinology |
Healthy: | No |
Age Range: | 18 - 65 |
Updated: | 4/2/2016 |
Start Date: | December 2007 |
End Date: | April 2015 |
Contact: | Monique Gagnon, B.A. |
Email: | monique.gagnon@va.gov |
Phone: | 858-552-8585 |
Phase 2 Study of the Assessment of the Insulin Sensitizing Activity of Fenretinide in Subjects With Insulin Resistance With BMI >30Kg/m2, and Liver Inflammation Related to Non-alcoholic Fatty Liver
Many metabolic complications of obesity are a consequence of abnormal responses of the
liver, muscle, and fat to insulin actions. Fenretinide may improve the effects of insulin,
preventing metabolic complications.
liver, muscle, and fat to insulin actions. Fenretinide may improve the effects of insulin,
preventing metabolic complications.
Inclusion Criteria:
- BMI >30
Exclusion Criteria:
- Diabetes Requiring Medication
- Poorly Controlled Co-Morbidities
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