Functional Connectivity Changes During Early Recovery as a Marker for Relapse
| Status: | Recruiting |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 3/1/2019 |
| Start Date: | July 2015 |
| End Date: | June 2020 |
| Contact: | Melanie Stimac |
| Email: | LNPIBrainStudy@umn.edu |
The study purpose is to examine whether there are structural or functional differences in the
brains of individuals who use cocaine or amphetamines as opposed to control participants who
have never used cocaine or amphetamines. More specifically, it will allow the investigator to
see how the brain changes once people get sober and how those changes relate to successful
recovery. This study will allow the investigator to examine the interaction between
cocaine/amphetamines and impulsivity (meaning to act on impulse rather than thought). Results
from this study will inform new biologically-based interventions to compliment existing
treatment programs, in the hope of leading the field in a new direction.
brains of individuals who use cocaine or amphetamines as opposed to control participants who
have never used cocaine or amphetamines. More specifically, it will allow the investigator to
see how the brain changes once people get sober and how those changes relate to successful
recovery. This study will allow the investigator to examine the interaction between
cocaine/amphetamines and impulsivity (meaning to act on impulse rather than thought). Results
from this study will inform new biologically-based interventions to compliment existing
treatment programs, in the hope of leading the field in a new direction.
Inclusion Criteria:
- At least 18 but no more than 45 years old at the time of consent.
- Able to provide written consent and comply with study procedures.
Exclusion Criteria:
- Any medical condition or treatment with neurological sequelae (i.e. stroke, tumor,
loss of consciousness for more than 30 minutes, seizures, HIV).
- Any contraindications to MRI scanning (i.e. metal implants, pacemakers, etc.).
- Intellectual developmental disorder as defined in the DSM-V. Participant may have a
diagnosis of an Axis I disorder (i.e. anxiety disorders, mood disorders, eating
disorders, psychotic disorders), but it must be considered stable.
- Actively suicidal.
- Positive screen for alcohol and/or drugs. Participants who screen positive for drugs
and/or alcohol may return at a later date to screen for the study again.
- Evidence for Wernicke-Korsakoff syndrome.
- Healthy Controls may never have had any form of substance use disorder other than
caffeine or nicotine. Nicotine use will be recorded but will not be an exclusion
criterion.
We found this trial at
1
site
Minneapolis, Minnesota 55455
(612) 625-5000
Principal Investigator: Kelvin O Lim, MD
Phone: 612-301-2449
Univ of Minnesota With a flagship campus in the heart of the Twin Cities, and...
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