OTX-16-002: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-TP in Subjects With Open-Angle Glaucoma and Ocular Hypertension

Inclusion Criteria:

- Documented diagnosis of ocular hypertension with an open angle of Schaffer Grade 3 or
greater or open-angle glaucoma without pseudoexfoliation or pigment dispersion or
evidence of traumatic angle recession

- IOP is currently controlled as assessed by the Investigator

Exclusion Criteria:

- Punctum size smaller than 0.4 mm or greater than 0.9 mm in either eye as measured
using a standard punctum gauge

- A history of an inadequate response or no response to topical prostaglandin

- Known or suspected allergy and/or hypersensitivity to travoprost or any prostaglandin,
fluorescein, or to any component of the study products