Primary Tumor Research and Outcome Network

Objective: To prospectively investigate the prognostic variables (clinical, diagnostic, and
therapeutic) within subgroups of patients diagnosed with primary spinal column tumors that
are associated with:

- survival

- local recurrence

- perioperative morbidity

- patient reported outcomes

Outcome measures: Variables applicable to primary spinal column tumor patients which will be
collected in the registry include:

- Patient details

- Treatment status

- Details of previous treatment

- Diagnosis and biopsy types

- Tumor details

- Oncological staging

- Symptoms

- Treatment details

- Imaging information

The investigators aim to collect the following outcome measures:

- Overall survival data

- Local disease recurrence data

- Perioperative morbidity data

Patient reported outcomes:

- Euroqual-5D-3L

- Euroquol EQ-5D VAS - Quality of Life

- Neck pain numeric rating scale (NRS)

- Arm pain NRS

- Back pain NRS

- Leg Pain NRS

- SF-36 version 2

- SOSG Outcome Questionnaire

Inclusion Criteria:

- Patient diagnosed with a primary tumor of the spine who receive medical and/or
surgical treatment for the tumor.

- Patient willing and able to participate in the registry and able to attend follow-up
visits, according to the investigator.

- Patient capable of understanding the content of the patient information and Informed
Consent Form (if consent is required by the EC/ IRB at the registry site).

- Patient who has agreed to participate in the registry by providing consent according
to the applicable local law and the declaration of Helsinki.

Exclusion Criteria:

- Patient diagnosed with a metastatic tumor of the spine.

- Patient diagnosed with a primary spinal cord tumor.