Smoking Cessation Intervention



Status:Suspended
Conditions:Smoking Cessation
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:1/19/2019
Start Date:December 13, 2016
End Date:July 2020

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Pilot Trial of a Smoking Cessation Intervention Informed by Construal Level Theory

Cigarette smoking is the leading cause of preventable mortality in the United States, yet
less than 10% of smokers making a serious quit attempt remain abstinent from cigarettes 1
year later, and outcomes from gold-standard behavioral interventions leave much room for
improvement. As such, in the context of a Stage-I randomized controlled trial (RCT), this
study will examine (1) treatment characteristics and delivery, treatment integrity, dropout,
and acceptability, (2) smoking outcomes such as lapse, relapse, and abstinence measures, and
(3) changes decision-making that result from a novel intervention informed by behavioral
analysis and social cognition.

Cigarette smoking is the leading cause of preventable mortality in the United States,
implicated in countless health consequences, and significant economic and societal costs.
Less than 10% of smokers making a serious quit attempt remain abstinent from cigarettes 1
year later, and outcomes from gold-standard behavioral interventions leave much room for
improvement. Thus the development of new interventions and improvements to existing
interventions is imperative. Behavioral interventions for smoking cessation have
insufficiently integrated the findings from basic research on decision-making processes.
Thus, there is extensive laboratory-based research indicating the potential for
laboratory-based manipulations that affect decision making relevant for smoking, the
examination of a coherent intervention that capitalizes on this knowledge is limited. The
proposed research is the first step toward synthesizing insights from the research domains of
addiction, behavioral analysis, and social cognition into a cohesive formulation with
potential impact on smoking cessation. Specifically, the research targets impulsive decision
making associated with cigarette smoking and relapse by incorporating the influential
Construal Level Theory.

Inclusion Criteria:

- Current cigarette smoker (verified with an expired carbon monoxide level of at least 4
ppm of expired air),

- At least 18 years of age,

- With a desire to quit smoking in the next month (at least 5 on a 10-point scale).

Exclusion Criteria:

- Pregnancy,

- Having uncontrolled serious psychiatric or medical illnesses,

- Having recent suicide attempts or ideation,

- Meeting contraindications for use of nicotine replacement products,

- Taking pharmocotherapy for smoking cessation treatment.
We found this trial at
1
site
Gainesville, Florida 32610
(352) 392-3261
Principal Investigator: Richard Yi, PhD
Phone: 352-294-1066
University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
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Gainesville, FL
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