To Evaluate the Safety and Pharmacokinetics of BMS-986177 in Healthy Japanese Participants



Status:Completed
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 55
Updated:6/3/2018
Start Date:June 28, 2017
End Date:November 7, 2017

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Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of BMS-986177 in Healthy Japanese Participants

Access the safety, tolerability, and pharmacokinetics of BMS-986177 in healthy Japanese
participants after multiple doses are administered.


Inclusion Criteria:

- Participants must be first-generation Japanese (born in Japan and not living outside
of Japan for > 10 years; both parents must be ethnically Japanese)

- Body Mass Index 18.0 to 25.0 kg/m2, inclusive

- Women must not be of nonchildbearing potential (cannot become pregnant)

Exclusion Criteria:

- Any significant acute or chronic medical illness

- History of allergy to BMS-986177 or other factor Xia inhibitors and/or formulation
excipients or history of any significant drug allergy (such as anaphylaxis or
hepatotoxicity)

- History or evidence of abnormal bleeding or coagulation disorder

Other protocol defined inclusion and exclusion criteria apply
We found this trial at
1
site
5630 West Cerritos Avenue
Anaheim, California 90630
Phone: 714-252-0700
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from
Anaheim, CA
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