To Evaluate the Safety and Pharmacokinetics of BMS-986177 in Healthy Japanese Participants
Status: | Completed |
---|---|
Conditions: | Cardiology |
Therapuetic Areas: | Cardiology / Vascular Diseases |
Healthy: | No |
Age Range: | 18 - 55 |
Updated: | 6/3/2018 |
Start Date: | June 28, 2017 |
End Date: | November 7, 2017 |
Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of BMS-986177 in Healthy Japanese Participants
Access the safety, tolerability, and pharmacokinetics of BMS-986177 in healthy Japanese
participants after multiple doses are administered.
participants after multiple doses are administered.
Inclusion Criteria:
- Participants must be first-generation Japanese (born in Japan and not living outside
of Japan for > 10 years; both parents must be ethnically Japanese)
- Body Mass Index 18.0 to 25.0 kg/m2, inclusive
- Women must not be of nonchildbearing potential (cannot become pregnant)
Exclusion Criteria:
- Any significant acute or chronic medical illness
- History of allergy to BMS-986177 or other factor Xia inhibitors and/or formulation
excipients or history of any significant drug allergy (such as anaphylaxis or
hepatotoxicity)
- History or evidence of abnormal bleeding or coagulation disorder
Other protocol defined inclusion and exclusion criteria apply
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