One vs. Two Hand Use After Stroke: Role of Task Requirements



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - Any
Updated:1/31/2018
Start Date:September 2016
End Date:December 2017

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To further develop interventions, the investigators need a better understanding of which task
requirements (i.e. size or weight of object, location in workspace, etc.) drive a person
after stroke to use 2 hands (as opposed to 1), and how the severity of their injury impacts
this relationship and compare this to reaching in age-matched healthy controls subjects. A
better understanding of this relationship will promote more informed development of
rehabilitative interventions. This study proposes to explore in people after stroke and
healthy controls: i.) how specific functional tasks requirements relate to 1 vs. 2 handed
use, and ii.) how stroke severity impacts this arm use. We are proposing to study 15
individuals more than 6 months after stroke in the CSU Motor Behavior Lab for a two x 3 hour
session of task-related reaching in sitting and 33 age matched (double sample size) healthy
controls. The investigators will systematically vary task requirements (i.e. object size or
weight, location in workspace, etc.), and record use of 1 versus 2 hands using videotaping as
well as recording of quality of arm movement (kinematics) and muscle activity (EMG) in both
arms.


Inclusion Criteria:

subjects post-stroke

- passive flexibility (i.e. passive range of motion) in both arms such that the elbows
can be straightened within 15 degrees of normal and shoulders be flexed (lifted up) at
least 90 degrees and the hand needs to be able to open at least 75% of the way

- Actively (of each subject's own accord/ability) they must be able to, without assist
in sitting and standing: straighten each elbow within 15 degrees of full range of
motion, lift each arm up at at least 60 degrees from at the side, open each hand from
a gross grasp volitionally.

- able to lift a glass jar using 1 or 2 hands in sitting and standing 10" above the
table top.

- able to come to CSU for two x 3 hour visits with or without assistance of their
caregiver/significant other

- No arm/hand injury within the last 3 months. * Individuals with common visual deficits
post-stroke (1 side partial visual field cut aka homonymous hemianopsia) will be
included.

Healthy controls:

-age matched (double sample size); no known injury to arms within last 3 months, able to
carry out experimental task, no neurologic diagnoses/perceptual or sensory deficits
affecting arm movement

Exclusion Criteria:

- Individuals who have any additional/other neurologic condition (i.e. Parkinsons
Disease, multiple sclerosis, spinal cord injury)

- severe perceptual neglect (tested using clock drawing test ).

- Any individual who cannot answer phone screen questions competently and/or follow
simple 2 step commands during the in-person screen
We found this trial at
1
site
Cleveland, Ohio 44115
Phone: 216-687-6988
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Cleveland, OH
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