Detection of Tumor DNA in Blood Samples From Cancer Patients
| Status: | Recruiting |
|---|---|
| Conditions: | Cancer, Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 8/10/2018 |
| Start Date: | December 2014 |
| End Date: | November 2020 |
| Contact: | Haluk Tezcan, MD |
| Email: | htezcan@lexentbio.com |
| Phone: | 530-863-7922 |
Detection of Tumor DNA in Blood Samples From Patients With Late Stage Cancer and "Healthy Controls"
The aim of this study is to employ genomic detection methodologies to measure the relative
amount of tumor nucleic acids in the blood of a cancer patient with diagnosed metastatic
disease that is either commencing, currently undergoing or completed cytotoxic chemotherapy
treatment. More generally, this approach will allow us to develop a quantitative measure of
therapy efficacy via the counting of the relative changes in tumor molecules over the course
of treatment.
amount of tumor nucleic acids in the blood of a cancer patient with diagnosed metastatic
disease that is either commencing, currently undergoing or completed cytotoxic chemotherapy
treatment. More generally, this approach will allow us to develop a quantitative measure of
therapy efficacy via the counting of the relative changes in tumor molecules over the course
of treatment.
Inclusion Criteria:
- Age 18 years or older
- Have metastatic disease with from a solid tumor (e.g. breast, lung, colon, pancreas,
ovary, prostate...) or stage II or III solid tumors undergoing curative surgery or
neoadjuvant therapy followed by surgery
- Starting treatment or a new line of treatment
- Able to understand and grant informed consent
- Able to have their blood drawn
Exclusion Criteria:
- Unable to grant informed consent or comply with all study procedures.
- Has a hematological malignancy, i.e. myeloma, lymphoma, MDS, leukemia
We found this trial at
4
sites
San Diego, California 92123
Principal Investigator: Shieh Marie, MD
Phone: 858-939-5062
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