Effects of Exercise Mode on Cardiac Fat, Function, and Geometry
| Status: | Recruiting |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - 35 |
| Updated: | 9/8/2018 |
| Start Date: | October 1, 2017 |
| End Date: | May 2019 |
| Contact: | Maria Fernandez del Valle, PhD |
| Email: | marfern@siue.edu |
| Phone: | (806) 834-5303 |
The overall goal of this project is to study the effects of exercise energy expenditure
matched vigorous dynamic resistance training and aerobic training on cardiac fat, and its
relationship to cardiac function and geometry using cardiac Magnetic Resonance Imaging.
matched vigorous dynamic resistance training and aerobic training on cardiac fat, and its
relationship to cardiac function and geometry using cardiac Magnetic Resonance Imaging.
Exercise-induced weight-loss is one of the most common strategies for reducing excess fat in
overweight and obese individuals. Although vigorous intensity may be more favorable promoting
positive cardiac adaptations compared to low-moderate intensity, evidence of the positive
effects of different exercise modes needs to be explored to allow for realistic comparisons
with other strategies. Research using cardiac Magnetic Resonance Imaging that compares the
effects of different modes of exercise - matched by exercise energy expenditure — on
epicardial adipose tissue and paracardial adipose tissue, and how these interventions modify
cardiac function and geometry have not been previously explored in obesity.
overweight and obese individuals. Although vigorous intensity may be more favorable promoting
positive cardiac adaptations compared to low-moderate intensity, evidence of the positive
effects of different exercise modes needs to be explored to allow for realistic comparisons
with other strategies. Research using cardiac Magnetic Resonance Imaging that compares the
effects of different modes of exercise - matched by exercise energy expenditure — on
epicardial adipose tissue and paracardial adipose tissue, and how these interventions modify
cardiac function and geometry have not been previously explored in obesity.
Inclusion Criteria:
- Sedentary
- Caucasian
- BMI >30 kg/m2 and < 39.9 kg/m2
Exclusion Criteria:
- Known cardiovascular, metabolic, pulmonary disease or conditions
- Muscular-skeletal injuries
- Taking medications that affect endocrine or cardiovascular function
- Hypertension
- Being engaged in low intensity strength training more than two times per week or
moderate-high intensity of any type of frequency
- Being pregnant
- Cigarette smoking
- Having non-removable pieces or devices incompatible with DXA and CMR assessment.
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