Sedative-Anxiolytic Effects on Simulated Driving Performance
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 1/10/2019 |
| Start Date: | September 15, 2017 |
| End Date: | August 31, 2019 |
| Contact: | Marion Coe |
| Email: | marion.coe@uky.edu |
| Phone: | 859-257-6488 |
Alprazolam and Simulated Driving Performance: Next Day Effects
This study evaluates the effect of anxiety drugs taken at night on the ability to drive a car
the next day. Participants will receive alprazolam, placebo, or zolpidem at night before bed
or in the morning before using a driving simulator to assess impairment.
the next day. Participants will receive alprazolam, placebo, or zolpidem at night before bed
or in the morning before using a driving simulator to assess impairment.
Inclusion Criteria:
- valid driver's license
- english-speaking and literate
Exclusion Criteria:
- using daily medication for chronic condition
- acute narrow angle glaucoma
- previous adverse experience with study drugs
- experiences motion sickness in response to driving simulator
- BMI > 30
- women who are pregnant, lactating, or planning on becoming pregnant
- regular use of tobacco products
- current substance use disorder
- clinically significant ECG
- current ongoing psychiatric disorder
We found this trial at
1
site
643 Maxwelton Court
Lexington, Kentucky 40508
Lexington, Kentucky 40508
Phone: 859-257-6488
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