Study of Gut Microbiome and Colorectal Tumors



Status:Completed
Conditions:Colorectal Cancer, Cancer, Hematology
Therapuetic Areas:Hematology, Oncology
Healthy:No
Age Range:18 - Any
Updated:10/1/2017
Start Date:November 23, 2011
End Date:April 25, 2015

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

The Gut Microbiota in Conventional and Serrated Precursors of Colorectal Cancer

Gut microbiota were assessed in 540 colonoscopy-screened adults by 16S rRNA gene sequencing
of stool samples. Investigators compared gut microbiota diversity, overall composition, and
normalized taxon abundance among these groups.

Colorectal cancer is a heterogeneous disease arising from at least two precursors-the
conventional adenoma (CA) and the serrated polyp. A relationship between the human gut
microbiota and colorectal cancer has been shown; however, its relationship to the different
early precursors of colorectal cancer is understudied. This study tested, for the first time,
the relationship of the gut microbiota to specific colorectal polyp types.

Inclusion Criteria:

- Both men and women who have visited a gastroenterologist or surgeon, aged 18 or older
will be included in this study.

- Both men and women residents in the United States, aged 18 or older will be included
in this study.

Exclusion Criteria:

- Women who are pregnant will be excluded from participating in this study

- Subjects on ongoing antibiotic therapy will be excluded from participating in this
study.
We found this trial at
1
site
New York University School of Medicine
550 1st Ave
New York, New York 10016
(212) 263-7300
New York University School of Medicine NYU School of Medicine has a proud history that...
?
mi
from
New York, NY
Click here to add this to my saved trials