Effects of Avocado Intake on the Nutritional Status of Families
| Status: | Recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 5 - Any |
| Updated: | 10/4/2017 |
| Start Date: | April 20, 2017 |
| End Date: | June 2018 |
| Contact: | Matthew A Allison, MD, MPH |
| Email: | mallison@ucsd.edu |
| Phone: | (858)642-3289 |
Avocados are an excellent source of fiber, potassium, magnesium, and poly- and
mono-unsaturated fats. They can be a nutrient dense component of healthful dietary patterns
and have the potential to improve the cardiovascular disease (CVD) risk profiles of families
in the United States (US). The proposed research plan will focus on the contribution of
avocado intake to the reduction in CVD risk of US families, by examining the effects of
avocado intake on the overall nutritional status of families. Of particular interest is
establishing these effects in ethnic populations such as Hispanics/Latinos. On average,
Hispanic/Latinos are at increased risk for metabolic diseases that predispose to CVD. This
6-month cluster randomized trial in Hispanic/Latino Americans aims to accurately determine
the impact of avocados on the overall dietary pattern of their families. Future research will
extend the results of the current trial to a larger sample of ethnically diverse families in
order to evaluate whether sustained changes occur in nutritional, cardiovascular and
metabolic health status.
mono-unsaturated fats. They can be a nutrient dense component of healthful dietary patterns
and have the potential to improve the cardiovascular disease (CVD) risk profiles of families
in the United States (US). The proposed research plan will focus on the contribution of
avocado intake to the reduction in CVD risk of US families, by examining the effects of
avocado intake on the overall nutritional status of families. Of particular interest is
establishing these effects in ethnic populations such as Hispanics/Latinos. On average,
Hispanic/Latinos are at increased risk for metabolic diseases that predispose to CVD. This
6-month cluster randomized trial in Hispanic/Latino Americans aims to accurately determine
the impact of avocados on the overall dietary pattern of their families. Future research will
extend the results of the current trial to a larger sample of ethnically diverse families in
order to evaluate whether sustained changes occur in nutritional, cardiovascular and
metabolic health status.
Specific Aim 1: To determine how avocados are incorporated into the family's dietary pattern
and impact selected measures of nutritional status:
1. To determine if avocado intake substitutes for, or adds to, other sources of calories in
the family diet.
2. To determine if avocado intake helps reduce between-meal snacking of family members.
3. To determine if avocados help families meet US Dietary Guidelines for recommended intake
of: poly- and monounsaturated fats; vegetables; fiber; selected nutrients (vitamins C, D
and E, Folate, Calcium, Magnesium, potassium, iron); lutein and other carotenoids.
Specific aim 2: To determine if increased avocado intake affects cardio-metabolic risk
factors to include lipids, glucose, insulin, and HbA1c.
and impact selected measures of nutritional status:
1. To determine if avocado intake substitutes for, or adds to, other sources of calories in
the family diet.
2. To determine if avocado intake helps reduce between-meal snacking of family members.
3. To determine if avocados help families meet US Dietary Guidelines for recommended intake
of: poly- and monounsaturated fats; vegetables; fiber; selected nutrients (vitamins C, D
and E, Folate, Calcium, Magnesium, potassium, iron); lutein and other carotenoids.
Specific aim 2: To determine if increased avocado intake affects cardio-metabolic risk
factors to include lipids, glucose, insulin, and HbA1c.
Inclusion Criteria:
1. Be part of a family that consists of at least 3 individuals, but no more than 8, who
reside in the same home
2. Self-identify as Latino or Hispanic
3. Be older than 5 years of age
Exclusion Criteria:
1. Families with members who have clinically severe chronic diseases requiring specific
diets (e.g. stage IV congestive heart failure, chronic kidney disease requiring
dialysis)
2. Those allergic to avocados
3. Those with LATEX allergy
4. Families who are already high consumers of avocados (i.e. more than 1 avocado per
adult and more than ½ avocado per child per day);
5. Those who are unwilling to eat avocados.
6. Family members with nursing or pregnant females or females planning to become pregnant
7. Family members under the age of 5 years will not be counted toward the number of
family members who will be expected to participate in the intervention (i.e., adhere
to healthy diet tips or consume avocados)
8. Families intending to move, or which include family members intending to move, within
the next 6 months
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