Comparison of MR Elastography Methods Without and With Compressed Sensing
| Status: | Completed |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 99 |
| Updated: | 1/31/2018 |
| Start Date: | August 15, 2017 |
| End Date: | December 1, 2017 |
In this research study, the investigators will compare the liver stiffness results obtained
from the current Magnetic Resonance Imaging (MRI) method to liver stiffness results obtained
from a method that uses faster imaging techniques.
from the current Magnetic Resonance Imaging (MRI) method to liver stiffness results obtained
from a method that uses faster imaging techniques.
MR elastography is increasingly used to assess liver stiffness in pediatric and adult
patients with chronic liver diseases. While numerous tissue abnormalities can affect liver
stiffness, liver stiffness measured by MR elastography is most often used to predict and
quantify liver fibrosis. Conventional MR elastography techniques require multiple
breath-holds that are 12-20 seconds in length. In the pediatric population, reliable
breath-holding >10 seconds can be challenging. Recently, compressed sensing has become
available as a method for accelerating image data acquisition, and thus shortening
breath-holds.
patients with chronic liver diseases. While numerous tissue abnormalities can affect liver
stiffness, liver stiffness measured by MR elastography is most often used to predict and
quantify liver fibrosis. Conventional MR elastography techniques require multiple
breath-holds that are 12-20 seconds in length. In the pediatric population, reliable
breath-holding >10 seconds can be challenging. Recently, compressed sensing has become
available as a method for accelerating image data acquisition, and thus shortening
breath-holds.
Inclusion Criteria:
- Adult volunteers ≥18 years of age
- Ability to tolerate 30 minutes in an MRI scanner.
- Nothing to eat or drink for 4 hours prior to the MRI scan
Exclusion Criteria:
- No contraindication to MR imaging (e.g., implanted non-MRI compatible device)
- Known or suspected pregnancy. Female subjects of child bearing potential will undergo
a urine pregnancy test prior to imaging.
We found this trial at
1
site
3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
Cincinnati, Ohio 45229
1-513-636-4200
Principal Investigator: Jonathan R Dillman, MSc,MD
Phone: 513-636-9403
Cincinnati Children's Hospital Medical Center Patients and families from across the region and around the...
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