Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee



Status:Completed
Conditions:Arthritis, Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:37 - Any
Updated:10/7/2017
Start Date:March 2007
End Date:October 2008

Use our guide to learn which trials are right for you!

Efficacy and Safety of the Lidocaine 5% Patch When Used as Adjunct Treatment in Patients With Osteoarthritis of the Knee Receiving Sub-Optimal Pain Relief From Their Current Analgesic Regimen

Patients with knee pain due to Osteoarthritis (OA) experiencing sub-optimal pain relief from
their current analgesic regimen will participate in a pilot clinical trial to evaluate the
effectiveness and tolerability of the Lidoderm Patch compared with placebo in treating knee
pain from OA.


Key Inclusion criteria:

- Male or female patients ≥37 years with moderate-to-severe OA related pain in one knee

- Body mass index (BMI) ≤40 kg/m2

- Symptomatic OA of the index knee diagnosed with a functional capacity of II or III
according to ACR criteria classification Note: Patients with symptomatic contralateral
knee OA with persistent pain ≤2 cm on a 0-10 cm PI-NRS for ≥2 months will be allowed
to participate.

- Unchanged dose of analgesic medication for OA for at least 4 weeks prior to screening
and for the duration of the study

- Able and willing to complete all paper and e-diary assessments required by protocol

Key Exclusion criteria:

- Pain in any joint other than the index joint that could interfere with the patient's
assessment of pain in the index joint

- Compromised integrity of the intact, superficial skin layer

- A grade 1 or 4 Kellgren and Lawrence score on radiographic examination

- Recent injury to either knee causing pain and interference with daily activities (eg.
walking)

- Recent surgery/procedure to either knee causing pain that could interfere with study
assessments of pain, function, and QoL

- Known hypersensitivity or allergy to lidocaine, local anesthetics of the amide type,
or any component of the product
We found this trial at
20
sites
Oklahoma City, Oklahoma 73103
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
175 Cross Keys Rd.
Berlin, New Jersey 08009
856-753-7335
?
mi
from
Berlin, NJ
Click here to add this to my saved trials
4460 Red Bank Expressway
Cincinnati, Ohio 45227
513-721-3868
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
2080 Bridgeport Avenue
Milford, Connecticut 06460
203-386-3115
?
mi
from
Milford, CT
Click here to add this to my saved trials
1701 E. Thomas Road
Phoenix, Arizona 85016
480-924-8382
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
?
mi
from
Beachwood, OH
Click here to add this to my saved trials
Clearwater, Florida 33761
?
mi
from
Clearwater, FL
Click here to add this to my saved trials
Delray Beach, Florida 33484
?
mi
from
Delray Beach, FL
Click here to add this to my saved trials
Duncansville, Pennsylvania 16635
?
mi
from
Duncansville, PA
Click here to add this to my saved trials
?
mi
from
Frederick, MD
Click here to add this to my saved trials
Lincoln, Nebraska 68516
?
mi
from
Lincoln, NE
Click here to add this to my saved trials
4550 East Bell Road
Paradise Valley, Arizona 85253
?
mi
from
Paradise Valley, AZ
Click here to add this to my saved trials
Phoenix, Arizona 85050
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Rapid City, South Dakota 57702
?
mi
from
Rapid City, SD
Click here to add this to my saved trials
Saint Peters, Missouri 63376
?
mi
from
Saint Peters, MO
Click here to add this to my saved trials
11201 Corporate Cir N
Saint Petersburg, Florida 33702
?
mi
from
Saint Petersburg, FL
Click here to add this to my saved trials
San Antonio, Texas
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
5115 North Armenia Avenue
Tampa, Florida 33603
?
mi
from
Tampa, FL
Click here to add this to my saved trials
Trumbull, Connecticut 06611
?
mi
from
Trumbull, CT
Click here to add this to my saved trials
1788 Republic Road
Virginia Beach, Virginia 23454
?
mi
from
Virginia Beach, VA
Click here to add this to my saved trials