Esophageal Motility and Airway Defenses Among Infants
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 10/8/2017 |
| Start Date: | May 2002 |
| End Date: | July 2005 |
Feeding difficulties and airway related consequences contribute significantly to the infant
mortality and morbidity. Some of these problems may be dependent on neural control and
muscular function. Prematurity, congenital anomalies and perinatal depression represent three
important conditions in infants, that may have feeding and airway difficulties.Development of
motility of the foregut and the adaptation during normal and disease in developing infants is
unclear.
mortality and morbidity. Some of these problems may be dependent on neural control and
muscular function. Prematurity, congenital anomalies and perinatal depression represent three
important conditions in infants, that may have feeding and airway difficulties.Development of
motility of the foregut and the adaptation during normal and disease in developing infants is
unclear.
With the aid of small clinical research funding from the NIDDK, in this proposal, we have
developed methods to safely evaluate foregut motility in relation to breathing among high
risk infants. We are using simultaneous esophageal motility studies, swallowing and
respiratory measurements in this evaluation.
developed methods to safely evaluate foregut motility in relation to breathing among high
risk infants. We are using simultaneous esophageal motility studies, swallowing and
respiratory measurements in this evaluation.
Inclusion Criteria:
Prematurely born infants, Infants with congenital foregut anomalies, Infants with perinatal
asphyxia, Ability to maintain vital signs at study,
Exclusion Criteria:
No contraindication to enteral feeding
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