Asthma Exacerbation Study

Inclusion Criteria:

- Clinical diagnosis of asthma

- Reversibility FEV1 of twelve percent or greater and two hundred milliliters and
greater approximately ten to forty minutes following two to four inhalations of
albuterol

- FEV1 of fifty to ninety percent of predicted

- Currently using inhaled corticosteroid therapy

- History of one or more asthma exacerbations requiring treatment with oral/systemic
corticosteroids or emergency department visit or in-patient hospitalization in
previous year

Exclusion Criteria:

- History of life threatening asthma in previous 5 years (requiring intubation, and/or
associated with hypercapnia, hypoxic seizure or respiratory arrest

- Respiratory infection or oral candidiasis

- - Uncontrolled disease or clinical abnormality

- Allergies

- Taking another investigational medication or prohibited medication