A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:40 - 55
Updated:10/20/2018
Start Date:May 26, 2016
End Date:October 31, 2017

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A Phase 2, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety, Efficacy, and Pharmacokinetics of the Fixed Combination of AGN-199201 and AGN-190584 in Patients With Presbyopia

This is a safety, efficacy and pharmacokinetics study of the fixed combination of AGN-199201
and AGN-190584 in participants with presbyopia (inability to focus on items close-up).


Inclusion Criteria:

- Normal vision at distance, either natural or post corneal laser refractive surgery,
with presbyopia in each eye and complaints of poor near vision that impacts activities
of daily living

Exclusion Criteria:

- Use of any topical ophthalmic medications, including artificial tears other than the
study medications during the study

- Corneal abnormalities in either eye that interfere with visual acuity

- History of cataract surgery, phakic intraocular lens surgery, corneal inlay surgery or
any intraocular surgery

- Diagnosis of glaucoma or ocular hypertension.
We found this trial at
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San Antonio, Texas 78229
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301 University Blvd
Galveston, Texas 77555
(409) 772-1011
University of Texas Medical Branch Established in 1891 as the University of Texas Medical Department,...
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301 West Huntington Drive
Arcadia, California 91007
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Artesia, California 90701
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1 Village Square
Baltimore, Maryland 21210
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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Cranberry Township, Pennsylvania 16066
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Cypress, California 90630
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El Paso, Texas 79902
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Glendale, California 91203
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Glendale, California 91205
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Louisville, Kentucky 40206
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Louisville, Kentucky 40206
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Memphis, Tennessee
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Miami, Florida 33143
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Morrow, Georgia 30260
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Newport Beach, California
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3133 Southwest 32nd Avenue
Ocala, Florida 34474
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Palo Alto, California 94303
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Portland, Oregon 97210
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San Antonio, Texas 78240
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Sarasota, Florida 34239
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23600 Telo Avenue
Torrance, California 90505
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Winston-Salem, North Carolina 27101
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