Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors



Status:Recruiting
Conditions:Breast Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:21 - Any
Updated:11/14/2018
Start Date:November 6, 2017
End Date:November 30, 2020
Contact:Horng-Shiuann Wu, Ph.D., RN
Email:hxw0198@bjc.org
Phone:314-454-8929

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Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors: A Personalized Intervention

This study will implement therapeutic bright light that is tailored to the individual's
circadian typology and will estimate its effects on circadian rhythms, 4 common
cancer-associated symptoms, and impact on quality of life in survivors living with cancer.
Examining a selected phase marker (core body temperature) in relation to the associated
clinical features (symptoms) is the starting point for future investigation of the biological
mechanisms of symptoms.


Inclusion Criteria:

- Females

- 21 years of age or older 1-3 years post-completion of chemotherapy or/and radiation
therapy for stage I-III breast cancer

- Experience ≥ 2 concurrent symptoms (fatigue, sleep disruption, depressive symptoms,
and/or cognitive dysfunction as measured by 4 screening instruments)

- Be either phase advanced or delayed (morning or evening types by the Horne-Ostberg
Morningness-Eveningness Questionnaire (MEQ) ≥59 or ≤41)

- Sighted

- Mentally competent to consent

- Able to understand English.

Exclusion Criteria:

- Undergoing cancer treatment for another malignancy

- Have metastatic cancer

- Engaged in shift work or travel across more than three time zones within 2 weeks prior
to study

- Current diagnosis of seasonal affective disorder or substance abuse Current diagnosis
of major Axis I psychiatric disorders (e.g. depressive disorders), neurological
impairments, or muscular dystrophies

- Report severe depressive mood (Center for Epidemiological Studies Depression Scale
(CES-D) >24)

- Take prescribed sedative hypnotics or steroids Have eye conditions (glaucoma or
retinal disease), problems triggered by bright light (e.g., migraine), or take
photosensitizing medications (e.g., some porphyrin drugs, antipsychotics,
antiarrhythmic agents)
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Horng-Shiuann Wu, Ph.D., RN
Phone: 314-454-8929
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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Saint Louis, MO
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