Pediatric Hypertension Registry (PHREG)



Status:Enrolling by invitation
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:Any - 17
Updated:6/28/2018
Start Date:September 20, 2017
End Date:October 20, 2027

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Pediatric hypertension is increasingly common and is a precursor for adult cardiovascular and
renal disease. But even during childhood, hypertension is associated with significant
morbidity, including cognitive impairment and organ damage. However, the cause of pediatric
hypertension, the response to treatment, and the mechanisms behind organ damage are
incompletely understood. Due to these limitations, there are no first-line medications, and
treatment is often inadequate. An improved comprehension of the course of pediatric
hypertension could enhance clinical care. The goal of this proposal is to create a registry
of patients with hypertension to better enable research into this important disease. This
patient registry will enhance the investigators ability to quickly collect and analyze data
for research studies.

The investigators will include all subjects evaluated at the Brenner Children's Hospital
Pediatric Nephrology clinic since January 1st, 2013 with a diagnosis of high blood pressure
confirmed with three separate blood pressure measurements >=90th percentile for age, sex, and
height, or >120/80 mmHg. The investigators will exclude patients whose initial evaluation
occurred on or after their 18th birthday.

Inclusion Criteria:

- Patients at the Wake Forest Baptist Health Brenner Children's Hospital Pediatric
Nephrology clinic

- Diagnosis of hypertension confirmed with three separate blood pressure measurements

- Diagnosis after January 2013

- >90th percentile for age, sex, height, or >120/80.

Exclusion Criteria:

- Patients whose initial evaluation occurred on or after their 18th birthday.
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