A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statins



Status:Completed
Conditions:High Cholesterol, High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:10/13/2017
Start Date:July 2011
End Date:June 2012

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 2, Double-blind, Placebo-controlled, Randomized Study To Assess The Efficacy, Safety And Tolerability Of Pf-04950615 Following Multiple Intravenous Doses In Hypercholesterolemic Subjects On High Doses Of Atorvastatin, Rosuvastatin Or Simvastatin.

This study will investigate the effect of PF-04950615, a new investigational lipid lowering
agent, on LDL-C and other lipids.


Inclusion Criteria:

- On a stable daily dose of atorvastatin, rosuvastatin or simvastatin.

- Lipids meet the following criteria at screening and prior to dosing: Fasting LDL-C
greater than 100 mg/dL and fasting TG less than 400 mg/dL

Exclusion Criteria:

- History of a cardiovascular or cerebrovascular event or procedure during the past
year.

- Poorly controlled type 1 or type 2 diabetes mellitus.

- Poorly controlled hypertension.
We found this trial at
39
sites
The Center for Pharmaceutical Research, P.C.
Kansas City, Missouri 64114
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Avail Clinical Research
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
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DeLand, FL
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Jacksonville Center for Clinical Research
4085 University Blvd S # 1
Jacksonville, Florida 32216
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Jacksonville, FL
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Commonwealth Biomedical Research, LLC
240 East Ayr Parkway
Madisonville, Kentucky 42431
888-569-8930
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Madisonville, KY
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Paragon Research Center
1148 E. Commerce St.
San Antonio, Texas 78205
(210) 340-5646
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San Antonio, TX
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Clinical Trials of Texas, Inc.
7940 Floyd Curl Dr.
San Antonio, Texas 78229
210-949-0122
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Spartanburg Medical Research
485 Simuel Road.
Spartanburg, South Carolina 29303
(864) 583-1556
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Spartanburg, SC
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Heartland Research Associates, LLC
1709 S Rock Rd
Wichita, Kansas 67207
316-689-6629
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Wichita, KS
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New Mexico Clinical Research & Osteoporosis Center, Incorporated
300 Oak Street Northeast
Albuquerque, New Mexico 87106
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Albuquerque, NM
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Maine Research Associates
Auburn, Maine 04210
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Auburn, ME
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Innovative Research of West Florida, Inc.
Clearwater, Florida 33756
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Clearwater, FL
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In Vivo Clinical Research
Doral, Florida 33166
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Doral, FL
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Altoona Center for Clinical Research
Duncansville, Pennsylvania 16635
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Texas Center for Drug Development, P.A.
Houston, Texas
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Houston, TX
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Saint Lukes Hospital
Kansas City, Missouri 64111
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Kansas City, MO
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Saint Luke's Lipid and Diabetes Research Center
Kansas City, Missouri
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The Medical Arts Health Research Group
Kelowna, British Columbia
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New Orleans Center for Clinical Research
Knoxville, Tennessee 37920
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Volunteer Research Group
Knoxville, Tennessee 37920
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L-MARC Research Center
Louisville, Kentucky 40213
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Louisville, KY
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Kendall South Medical Center, Inc.
Miami, Florida 33175
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Miami, FL
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National Clinical Research - Norfolk, Inc.
Norfolk, Virginia 23502
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Norfolk, VA
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Infinity Medical Research, Inc.
North Dartmouth, Massachusetts 02747
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North Dartmouth, MA
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Lynn Health Science Institute
3555 NW 58th St # 800
Oklahoma City, Oklahoma 73112
(405) 447-8839
Lynn Health Science Institute Our mission is to provide clinical trials research and health services...
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Oklahoma Cardiovascular Research Group (OCRG)
Oklahoma City, Oklahoma 73120
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Oklahoma Heart Hospital Physicians
Oklahoma City, Oklahoma 73120
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Oklahoma Heart Hospital
Oklahoma City, Oklahoma 73120
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Vince and Associates Clinical Research
Overland Park, Kansas 23112
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Overland Park, KS
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Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania 19104
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Philadelphia, PA
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Translational Research Center
3400 Civic Center Boulevard
Philadelphia, Pennsylvania 19104
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North Carolina Clinical Research
Raleigh, North Carolina 27607
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Raleigh, NC
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National Clinical Research - Richmond, Inc.
Richmond, Virginia 23294
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Richmond, VA
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Medex Healthcare Research, Inc.
Saint Louis, Missouri 63117
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Saint Louis, MO
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Pmg Research Of Salisbury
Salisbury, North Carolina 28144
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Salisbury, NC
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San Antonio Preventive & Diagnostic Medicine, PA
8401 Datapoint Drive
San Antonio, Texas 78229
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Orange County Research Center
Tustin, California
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Diablo Clinical Research Inc
Walnut creek, California 94598
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North Georgia Clinical Research
Woodstock, Georgia 30189
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North Georgia Internal Medicine
Woodstock, Georgia 30189
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Woodstock, GA
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