Study Of GW679769 In Major Depressive Disorder



Status:Completed
Conditions:Depression, Depression, Major Depression Disorder (MDD)
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 64
Updated:10/14/2017
Start Date:October 2004
End Date:September 2006

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed-Dose Study Evaluating the Efficacy and Safety of GW679769 in Subjects With Major Depressive Disorder.

This is a placebo-controlled, fixed dose study that will evaluate the efficacy and safety of
GW679769 in subjects with major depressive disorder.


Inclusion criteria:

- Subjects must have the ability to comprehend the key components of the consent form.

- Subject must have met DSM-IV-TR (Diagnostic and Statistical Manual of Mental
Disorders, Fourth Edition, Text Revision) criteria for current MDE (major depressive
episode) for at least 8 weeks prior to the Screening Visit.

- If female, subjects must be practicing an acceptable method of birth control.

- Subjects must have rating scores as outlined.

Exclusion criteria:

- Subjects whose symptoms of the MDE are better accounted for by another diagnosis.

- Subjects with a history of schizophrenia, schizoaffective disorders or bipolar
disorder.

- Subjects have a positive urine test for illicit drug use and/or a history of substance
abuse or alcohol dependence within the past 12 months.

- Subjects with an unstable medical disorder.

- If female, pregnant or lactating.

- Subjects who have received ECT (electroconvulsive therapy) or TMS (transcranial
magnetic stimulation) within the 6 months preceding screening or who have ever been
homicidal.
We found this trial at
27
sites
GSK Investigational Site
Scottsdale, Arizona 85259
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Scottsdale, AZ
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GSK Investigational Site
Austin, Texas 78705
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Austin, TX
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GSK Investigational Site
Beachwood, Ohio 44122
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Beachwood, OH
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GSK Investigational Site
Bellevue, Washington 98004
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Bellevue, WA
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GSK Investigational Site
Beverly Hills, California 90211
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Beverly Hills, CA
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GSK Investigational Site
Brooklyn, New York 11215
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Brooklyn, NY
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GSK Investigational Site
Clementon, New Jersey 08021
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Clementon, NJ
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GSK Investigational Site
Edmonton, Alberta
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Edmonton,
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GSK Investigational Site
Eugene, Oregon 97401
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Eugene, OR
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GSK Investigational Site
Farmington Hills, Michigan 48334
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Farmington Hills, MI
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GSK Investigational Site
Fort Lauderdale, Florida 33308
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Fort Lauderdale, FL
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GSK Investigational Site
Irving, Texas 75039
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Irving, TX
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GSK Investigational Site
Lake Jackson, Texas 77566
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Lake Jackson, TX
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GSK Investigational Site
Little Rock, Arkansas 72205
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Little Rock, AR
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GSK Investigational Site
Marietta, Georgia 30060
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Marietta, GA
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GSK Investigational Site
Memphis, Tennessee 38120
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Memphis, TN
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GSK Investigational Site
Miami, Florida 33136
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Miami, FL
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GSK Investigational Site
New York, New York 10032
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New York, NY
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GSK Investigational Site
North Miami, Florida 33161
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North Miami, FL
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GSK Investigational Site
Oakbrook Terrace, Illinois 60181
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Oakbrook Terrace, IL
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GSK Investigational Site
Orlando, Florida 32806
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Orlando, FL
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GSK Investigational Site
Portland, Oregon 97227
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Portland, OR
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GSK Investigational Site
Rockville, Maryland 20850
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Rockville, MD
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GSK Investigational Site
Shreveport, Louisiana 71103
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Shreveport, LA
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GSK Investigational Site
Smyrna, Georgia 30080
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Smyrna, GA
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GSK Investigational Site
St. Charles, Missouri 63301
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St. Charles, MO
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GSK Investigational Site
Winter Park, Florida 32789
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Winter Park, FL
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