COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria



Status:Terminated
Conditions:High Blood Pressure (Hypertension), Cardiology, Endocrine
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology
Healthy:No
Age Range:18 - 80
Updated:10/14/2017
Start Date:July 2005
End Date:May 2006

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-blind, Positive-Controlled, Multicenter Study Comparing the Efficacy of Carvedilol Phosphate Modified Release Formulation (COREG MR) and Metoprolol Succinate Extended Release (TOPROL-XL) on the Reduction of Microalbuminuria in Patients With Hypertension and Microalbuminuria

This study was designed to determine whether COREG MR is more effective than TOPROL-XL in
reducing microalbuminuria in type 2 diabetic or non-diabetic patients with high blood
pressure and microalbuminuria.


Inclusion criteria:

- Documented history of hypertension.

- Must have been taking an ACE (angiotensin converting enzyme) inhibitor either alone or
as part of an antihypertensive regimen for at least 8 weeks.

- Persistent microalbuminuria.

Exclusion criteria:

- History of heart attack, stroke, congestive heart failure, arrhythmia, type 1 or
uncontrolled type 2 diabetes mellitus, liver or renal disease.

- Has been taking any non-ocular beta-blockers for any indication within three months
prior to Pre-screening.
We found this trial at
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Spokane, Washington 99208
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Avon, Indiana 46123
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Ayer, Massachusetts 01432
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Beaumont, Texas 77701
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Beaver, Pennsylvania 15009
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Birmingham, Alabama 35249
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Buffalo, New York 14263
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Burke, Virginia 22015
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Calgary, Alberta
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Camillus, New York 13031
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Charlotte, North Carolina 28203
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Chicago, Illinois 60611
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Cleveland, Ohio 44195
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Colorado Springs, Colorado 80910
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Columbus, Ohio 43219
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Dallas, Texas 75230
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Decatur, Georgia 30033
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East Providence, Rhode Island 02914
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East Syracuse, New York 13057
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Edmonds, Washington 98026
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Elkhart, Indiana 46514
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Evansville, Indiana 47714
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Fort Worth, Texas 76104
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Fullerton, California 92835
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Galveston, Texas 77555
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Greensboro, North Carolina 27403
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Greer, South Carolina 29651
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Havertown, Pennsylvania 19083
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Hollywood, Florida 33021
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Houston, Texas 77030
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Indianapolis, Indiana 46202
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Inglewood, California 90301
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Johnson City, Tennessee 37601
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Kettering, Ohio 45429
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Kingston, New York 12401
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Lafayette, Louisiana 70503
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Las Vegas, Nevada 89102
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Los Angeles, California 90025
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Melrose Park, Illinois 60160
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Miami, Florida 33136
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Midland, Texas 79701
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Mission Viejo, California 92691
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Mobile, Alabama 36617
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Oakland, California 94611
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Oklahoma City, Oklahoma 73112
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Olympia, Washington 98506
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Orangeburg, South Carolina 29118
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Oregon City, Oregon 97045
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Pembroke Pines, Florida 33028
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Philadelphia, Pennsylvania 19104
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Phoenix, Arizona 85012
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Port Chester, New York 10573
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Raleigh, North Carolina 27614
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Reading, Pennsylvania 19611
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Redondo Beach, California 90277
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Rochester, New York 14642
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San Antonio, Texas 78258
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Sarasota, Florida 34232
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Springfield, Virginia 22151
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Tampa, Florida 33612
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Voorhees, New Jersey 08043
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Wenatchee, Washington 98801
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West Grove, Pennsylvania 19390
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Worcester, Massachusetts 01655
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