Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks



Status:Completed
Conditions:Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:12/7/2017
Start Date:October 2005
End Date:June 2006

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A Randomized, Double-blind, Multi-center, Placebo-controlled, Cross-over Study to Determine the Consistency of Response for Trexima (Sumatriptan 85mg/Naproxen Sodium 500mg) Administered During the Mild Pain Phase for the Acute Treatment of Multiple Migraine Attacks

The purpose of this study is to determine the consistency of response for Treximet
(sumatriptan/naproxen sodium), formerly known as Trexima, when treating four acute migraine
attacks at the mild pain phase and within 1 hour of onset of head pain.


Inclusion Criteria:

- At least a 6 month history of physician diagnosed migraine and typically experiences
2-6 migraine attacks per month.

- Typically experiences moderate to severe migraine pain preceded by a mild pain phase.

- Differentiate between mild migraine pain and other headache types.

- Women of childbearing potential must be on adequate contraception.

Exclusion Criteria:

- Pregnant and/or nursing mother.

- History of cardiovascular disease.

- Uncontrolled hypertension.

- Basilar or Hemiplegic migraine.

- History of stroke or transient ischemic attacks (TIA).

- History of epilepsy or treated with anti-epileptics within past 5 years.

- Impaired hepatic or renal function.

- History of gastrointestinal bleeding or ulceration.

- Allergy or hypersensitivity to Aspirin or any other NSAID.

- Allergy or hypersensitivity to triptans.

- Participated in an investigational drug trial in the previous 4 weeks.
We found this trial at
48
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Milford, Massachusetts 01757
432
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Milford, MA
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Atlanta, Georgia 30341
614
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Austell, Georgia 30106
626
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Austell, GA
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Austin, Texas 78705
1279
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Austin, TX
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Braintree, Massachusetts 02184
458
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Braintree, MA
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Burlington, Vermont 05401
376
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Burlington, VT
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Chandler, Arizona 85224
1834
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Chandler, AZ
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Chicago, Illinois 60611
393
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Chicago, IL
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Cleveland, Ohio 44195
95
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Cleveland, OH
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Colorado Springs, Colorado 80910
1319
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Colorado Springs, CO
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Daytona Beach, Florida 32117
891
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Daytona Beach, FL
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Endwell, New York 13760
201
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Endwell, NY
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Eugene, Oregon 97401
2155
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Eugene, OR
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Fargo, North Dakota 58122
911
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Fargo, ND
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Fort Wayne, Indiana 46825
274
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Fort Wayne, IN
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Georgetown, Texas 78626
1260
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Georgetown, TX
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Germantown, Tennessee 38138
718
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Germantown, TN
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Hartford, Connecticut 06105
373
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Hartford, CT
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Hollywood, Florida 33021
1111
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Hollywood, FL
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Houston, Texas 77030
1213
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Houston, TX
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Irvine, California 92697
2128
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Irvine, CA
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Kalamazoo, Michigan 49007
288
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Kalamazoo, MI
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Las Vegas, Nevada 89102
1918
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Las Vegas, NV
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Little Rock, Arkansas 72205
840
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Little Rock, AR
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Manhasset, New York 11030
336
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Manlius, New York 13104
211
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Medford, Oregon 97504
2172
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Medford, OR
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Minneapolis, Minnesota 55404
694
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Minneapolis, MN
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Mount Pleasant, South Carolina 29464
643
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Mount Pleasant, SC
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Nashville, Tennessee 37203
550
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Nashville, TN
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New York, New York 10032
323
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New York, NY
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Newport Beach, California 92663
2133
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Newport Beach, CA
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Oklahoma City, Oklahoma 73112
1049
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Oklahoma City, OK
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Palm Beach Gardens, Florida 33410
1056
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Philadelphia, Pennsylvania 19104
288
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Philadelphia, PA
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Phoenix, Arizona 85012
1838
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Pittsburgh, Pennsylvania 15213
115
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Salt Lake City, Utah 84132
1644
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San Antonio, Texas 78258
1342
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San Francisco, California 94115
2246
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Santa Monica, California 90404
2148
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Seattle, Washington 98109
2083
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Stamford, Connecticut 06902
339
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Tulsa, Oklahoma 74105
951
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Walnut Creek, California 94596
2223
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West Palm Beach, Florida 33409
1063
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Westlake Village, California 91361
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Wichita, Kansas 67207
964
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Wichita, KS
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