Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks



Status:Completed
Conditions:Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:12/7/2017
Start Date:October 2005
End Date:June 2006

Use our guide to learn which trials are right for you!

A Randomized, Double-blind, Multi-center, Placebo-controlled, Cross-over Study to Determine the Consistency of Response for Trexima (Sumatriptan 85mg/Naproxen Sodium 500mg) Administered During the Mild Pain Phase for the Acute Treatment of Multiple Migraine Attacks

The purpose of this study is to determine the consistency of response for Treximet
(sumatriptan/naproxen sodium), formerly known as Trexima, when treating four acute migraine
attacks at the mild pain phase and within 1 hour of onset of head pain.


Inclusion Criteria:

- At least a 6 month history of physician diagnosed migraine and typically experiences
2-6 migraine attacks per month.

- Typically experiences moderate to severe migraine pain preceded by a mild pain phase.

- Differentiate between mild migraine pain and other headache types.

- Women of childbearing potential must be on adequate contraception.

Exclusion Criteria:

- Pregnant and/or nursing mother.

- History of cardiovascular disease.

- Uncontrolled hypertension.

- Basilar or Hemiplegic migraine.

- History of stroke or transient ischemic attacks (TIA).

- History of epilepsy or treated with anti-epileptics within past 5 years.

- Impaired hepatic or renal function.

- History of gastrointestinal bleeding or ulceration.

- Allergy or hypersensitivity to Aspirin or any other NSAID.

- Allergy or hypersensitivity to triptans.

- Participated in an investigational drug trial in the previous 4 weeks.
We found this trial at
48
sites
Las Vegas, Nevada 89102
2369
mi
from 02139
Las Vegas, NV
Click here to add this to my saved trials
Atlanta, Georgia 30341
923
mi
from 02139
Atlanta, GA
Click here to add this to my saved trials
Austell, Georgia 30106
941
mi
from 02139
Austell, GA
Click here to add this to my saved trials
Austin, Texas 78705
1690
mi
from 02139
Austin, TX
Click here to add this to my saved trials
Braintree, Massachusetts 02184
11
mi
from 02139
Braintree, MA
Click here to add this to my saved trials
Burlington, Vermont 05401
180
mi
from 02139
Burlington, VT
Click here to add this to my saved trials
Chandler, Arizona 85224
2286
mi
from 02139
Chandler, AZ
Click here to add this to my saved trials
Chicago, Illinois 60611
845
mi
from 02139
Chicago, IL
Click here to add this to my saved trials
Cleveland, Ohio 44195
543
mi
from 02139
Cleveland, OH
Click here to add this to my saved trials
Colorado Springs, Colorado 80910
1771
mi
from 02139
Colorado Springs, CO
Click here to add this to my saved trials
Daytona Beach, Florida 32117
1063
mi
from 02139
Daytona Beach, FL
Click here to add this to my saved trials
Endwell, New York 13760
252
mi
from 02139
Endwell, NY
Click here to add this to my saved trials
Eugene, Oregon 97401
2576
mi
from 02139
Eugene, OR
Click here to add this to my saved trials
Fargo, North Dakota 58122
1315
mi
from 02139
Fargo, ND
Click here to add this to my saved trials
Fort Wayne, Indiana 46825
726
mi
from 02139
Fort Wayne, IN
Click here to add this to my saved trials
Georgetown, Texas 78626
1673
mi
from 02139
Georgetown, TX
Click here to add this to my saved trials
Germantown, Tennessee 38138
1122
mi
from 02139
Germantown, TN
Click here to add this to my saved trials
Hartford, Connecticut 06105
91
mi
from 02139
Hartford, CT
Click here to add this to my saved trials
Hollywood, Florida 33021
1240
mi
from 02139
Hollywood, FL
Click here to add this to my saved trials
Houston, Texas 77030
1605
mi
from 02139
Houston, TX
Click here to add this to my saved trials
Irvine, California 92697
2580
mi
from 02139
Irvine, CA
Click here to add this to my saved trials
Kalamazoo, Michigan 49007
738
mi
from 02139
Kalamazoo, MI
Click here to add this to my saved trials
Little Rock, Arkansas 72205
1258
mi
from 02139
Little Rock, AR
Click here to add this to my saved trials
Manhasset, New York 11030
172
mi
from 02139
Manhasset, NY
Click here to add this to my saved trials
Manlius, New York 13104
251
mi
from 02139
Manlius, NY
Click here to add this to my saved trials
Medford, Oregon 97504
2601
mi
from 02139
Medford, OR
Click here to add this to my saved trials
Milford, Massachusetts 01757
26
mi
from 02139
Milford, MA
Click here to add this to my saved trials
Minneapolis, Minnesota 55404
1118
mi
from 02139
Minneapolis, MN
Click here to add this to my saved trials
Mount Pleasant, South Carolina 29464
815
mi
from 02139
Mount Pleasant, SC
Click here to add this to my saved trials
Nashville, Tennessee 37203
940
mi
from 02139
Nashville, TN
Click here to add this to my saved trials
New York, New York 10032
180
mi
from 02139
New York, NY
Click here to add this to my saved trials
Newport Beach, California 92663
2586
mi
from 02139
Newport Beach, CA
Click here to add this to my saved trials
Oklahoma City, Oklahoma 73112
1492
mi
from 02139
Oklahoma City, OK
Click here to add this to my saved trials
Palm Beach Gardens, Florida 33410
1188
mi
from 02139
Palm Beach Gardens, FL
Click here to add this to my saved trials
Philadelphia, Pennsylvania 19104
270
mi
from 02139
Philadelphia, PA
Click here to add this to my saved trials
Phoenix, Arizona 85012
2290
mi
from 02139
Phoenix, AZ
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15213
477
mi
from 02139
Pittsburgh, PA
Click here to add this to my saved trials
Salt Lake City, Utah 84132
2088
mi
from 02139
Salt Lake City, UT
Click here to add this to my saved trials
San Antonio, Texas 78258
1752
mi
from 02139
San Antonio, TX
Click here to add this to my saved trials
San Francisco, California 94115
2691
mi
from 02139
San Francisco, CA
Click here to add this to my saved trials
Santa Monica, California 90404
2600
mi
from 02139
Santa Monica, CA
Click here to add this to my saved trials
Seattle, Washington 98109
2483
mi
from 02139
Seattle, WA
Click here to add this to my saved trials
Stamford, Connecticut 06902
155
mi
from 02139
Stamford, CT
Click here to add this to my saved trials
Tulsa, Oklahoma 74105
1393
mi
from 02139
Tulsa, OK
Click here to add this to my saved trials
Walnut Creek, California 94596
2667
mi
from 02139
Walnut Creek, CA
Click here to add this to my saved trials
West Palm Beach, Florida 33409
1194
mi
from 02139
West Palm Beach, FL
Click here to add this to my saved trials
Westlake Village, California 91361
2614
mi
from 02139
Westlake Village, CA
Click here to add this to my saved trials
Wichita, Kansas 67207
1414
mi
from 02139
Wichita, KS
Click here to add this to my saved trials