Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks



Status:Completed
Conditions:Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:12/7/2017
Start Date:October 2005
End Date:June 2006

Use our guide to learn which trials are right for you!

A Randomized, Double-blind, Multi-center, Placebo-controlled, Cross-over Study to Determine the Consistency of Response for Trexima (Sumatriptan 85mg/Naproxen Sodium 500mg) Administered During the Mild Pain Phase for the Acute Treatment of Multiple Migraine Attacks

The purpose of this study is to determine the consistency of response for Treximet
(sumatriptan/naproxen sodium), formerly known as Trexima, when treating four acute migraine
attacks at the mild pain phase and within 1 hour of onset of head pain.


Inclusion Criteria:

- At least a 6 month history of physician diagnosed migraine and typically experiences
2-6 migraine attacks per month.

- Typically experiences moderate to severe migraine pain preceded by a mild pain phase.

- Differentiate between mild migraine pain and other headache types.

- Women of childbearing potential must be on adequate contraception.

Exclusion Criteria:

- Pregnant and/or nursing mother.

- History of cardiovascular disease.

- Uncontrolled hypertension.

- Basilar or Hemiplegic migraine.

- History of stroke or transient ischemic attacks (TIA).

- History of epilepsy or treated with anti-epileptics within past 5 years.

- Impaired hepatic or renal function.

- History of gastrointestinal bleeding or ulceration.

- Allergy or hypersensitivity to Aspirin or any other NSAID.

- Allergy or hypersensitivity to triptans.

- Participated in an investigational drug trial in the previous 4 weeks.
We found this trial at
48
sites
Minneapolis, Minnesota 55404
1392
mi
from 98109
Minneapolis, MN
Click here to add this to my saved trials
Atlanta, Georgia 30341
2176
mi
from 98109
Atlanta, GA
Click here to add this to my saved trials
Austell, Georgia 30106
2165
mi
from 98109
Austell, GA
Click here to add this to my saved trials
Austin, Texas 78705
1769
mi
from 98109
Austin, TX
Click here to add this to my saved trials
Braintree, Massachusetts 02184
2492
mi
from 98109
Braintree, MA
Click here to add this to my saved trials
Burlington, Vermont 05401
2325
mi
from 98109
Burlington, VT
Click here to add this to my saved trials
Chandler, Arizona 85224
1128
mi
from 98109
Chandler, AZ
Click here to add this to my saved trials
Chicago, Illinois 60611
1733
mi
from 98109
Chicago, IL
Click here to add this to my saved trials
Cleveland, Ohio 44195
2024
mi
from 98109
Cleveland, OH
Click here to add this to my saved trials
Colorado Springs, Colorado 80910
1070
mi
from 98109
Colorado Springs, CO
Click here to add this to my saved trials
Daytona Beach, Florida 32117
2528
mi
from 98109
Daytona Beach, FL
Click here to add this to my saved trials
Endwell, New York 13760
2265
mi
from 98109
Endwell, NY
Click here to add this to my saved trials
Eugene, Oregon 97401
249
mi
from 98109
Eugene, OR
Click here to add this to my saved trials
Fargo, North Dakota 58122
1172
mi
from 98109
Fargo, ND
Click here to add this to my saved trials
Fort Wayne, Indiana 46825
1872
mi
from 98109
Fort Wayne, IN
Click here to add this to my saved trials
Georgetown, Texas 78626
1754
mi
from 98109
Georgetown, TX
Click here to add this to my saved trials
Germantown, Tennessee 38138
1877
mi
from 98109
Germantown, TN
Click here to add this to my saved trials
Hartford, Connecticut 06105
2428
mi
from 98109
Hartford, CT
Click here to add this to my saved trials
Hollywood, Florida 33021
2720
mi
from 98109
Hollywood, FL
Click here to add this to my saved trials
Houston, Texas 77030
1892
mi
from 98109
Houston, TX
Click here to add this to my saved trials
Irvine, California 92697
994
mi
from 98109
Irvine, CA
Click here to add this to my saved trials
Kalamazoo, Michigan 49007
1816
mi
from 98109
Kalamazoo, MI
Click here to add this to my saved trials
Las Vegas, Nevada 89102
874
mi
from 98109
Las Vegas, NV
Click here to add this to my saved trials
Little Rock, Arkansas 72205
1779
mi
from 98109
Little Rock, AR
Click here to add this to my saved trials
Manhasset, New York 11030
2413
mi
from 98109
Manhasset, NY
Click here to add this to my saved trials
Manlius, New York 13104
2241
mi
from 98109
Manlius, NY
Click here to add this to my saved trials
Medford, Oregon 97504
367
mi
from 98109
Medford, OR
Click here to add this to my saved trials
Milford, Massachusetts 01757
2471
mi
from 98109
Milford, MA
Click here to add this to my saved trials
Mount Pleasant, South Carolina 29464
2426
mi
from 98109
Mount Pleasant, SC
Click here to add this to my saved trials
Nashville, Tennessee 37203
1971
mi
from 98109
Nashville, TN
Click here to add this to my saved trials
New York, New York 10032
2400
mi
from 98109
New York, NY
Click here to add this to my saved trials
Newport Beach, California 92663
995
mi
from 98109
Newport Beach, CA
Click here to add this to my saved trials
Oklahoma City, Oklahoma 73112
1519
mi
from 98109
Oklahoma City, OK
Click here to add this to my saved trials
Palm Beach Gardens, Florida 33410
2683
mi
from 98109
Palm Beach Gardens, FL
Click here to add this to my saved trials
Philadelphia, Pennsylvania 19104
2371
mi
from 98109
Philadelphia, PA
Click here to add this to my saved trials
Phoenix, Arizona 85012
1112
mi
from 98109
Phoenix, AZ
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15213
2134
mi
from 98109
Pittsburgh, PA
Click here to add this to my saved trials
Salt Lake City, Utah 84132
702
mi
from 98109
Salt Lake City, UT
Click here to add this to my saved trials
San Antonio, Texas 78258
1776
mi
from 98109
San Antonio, TX
Click here to add this to my saved trials
San Francisco, California 94115
680
mi
from 98109
San Francisco, CA
Click here to add this to my saved trials
Santa Monica, California 90404
961
mi
from 98109
Santa Monica, CA
Click here to add this to my saved trials
Seattle, Washington 98109
0
mi
from 98109
Seattle, WA
Click here to add this to my saved trials
Stamford, Connecticut 06902
2412
mi
from 98109
Stamford, CT
Click here to add this to my saved trials
Tulsa, Oklahoma 74105
1561
mi
from 98109
Tulsa, OK
Click here to add this to my saved trials
Walnut Creek, California 94596
673
mi
from 98109
Walnut Creek, CA
Click here to add this to my saved trials
West Palm Beach, Florida 33409
2690
mi
from 98109
West Palm Beach, FL
Click here to add this to my saved trials
Westlake Village, California 91361
949
mi
from 98109
Westlake Village, CA
Click here to add this to my saved trials
Wichita, Kansas 67207
1440
mi
from 98109
Wichita, KS
Click here to add this to my saved trials