Onset Motor Complications Using REQUIP CR (Ropinirole Controlled-release) As Add-on Therapy To L-dopa In Parkinson's



Status:Completed
Conditions:Parkinsons Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:30 - 70
Updated:10/14/2017
Start Date:December 2003
End Date:January 2006

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Trial Summary
Trial Overview
Inclusion Criteria

A Two Year Phase IIIb Randomised, Multicenter, Double-blind, SINEMET Controlled, Parallel Group, Flexible Dose Study, to Assess the Effectiveness of Controlled Release Ropinirole add-on Therapy to L-dopa at Increasing the Time to Onset of Dyskinesia in Parkinson's Disease Subjects.

This study evaluates how effective a new formulation of a marketed drug is in increasing the
time to onset of dyskinesia (abnormal twisting, writhing movements) in patients with
Parkinson's Disease who have been taking levodopa for less than 2 years.


Inclusion Criteria:

- Must be on 600mg or less of levodopa therapy for two years or less.

- Must be on a stable dose of levodopa therapy for at least 4 weeks prior to screening.

Exclusion Criteria:

- Current or past history of Dyskinesia.

- State of dementia or have a MMSE score < 26 at screening.
We found this trial at
65
sites
GSK Investigational Site
Amherst, New York 14226
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Amherst, NY
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Albany, New York 12206
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Albany, NY
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Alexandria, Virginia 22304
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Alexandria, VA
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Anniston, Alabama 36207
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Anniston, AL
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Asheville, North Carolina 28803
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Asheville, NC
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Augusta, Georgia 30909
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Augusta, GA
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Austell, Georgia 30106
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Austell, GA
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GSK Investigational Site
Austin, Texas 78705
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Austin, TX
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GSK Investigational Site
Bingham Farms, Michigan 48025
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Bingham Farms, MI
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GSK Investigational Site
Birmingham, Alabama 35249
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Birmingham, AL
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GSK Investigational Site
Boca Raton, Florida 33486
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Boca Raton, FL
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GSK Investigational Site
Boise, Idaho 83712
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Boise, ID
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GSK Investigational Site
Boulder, Colorado 80304
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Boulder, CO
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GSK Investigational Site
Chapel Hill, North Carolina 27599
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Chapel Hill, NC
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GSK Investigational Site
Charleston, West Virginia 25304
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Charleston, WV
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GSK Investigational Site
Chicago, Illinois 60611
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Chicago, IL
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GSK Investigational Site
Cincinnati, Ohio 45229
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Cincinnati, OH
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GSK Investigational Site
Columbus, Georgia 31904
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Columbus, GA
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GSK Investigational Site
Dallas, Texas 75230
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Dallas, TX
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GSK Investigational Site
Danbury, Connecticut 06810
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Danbury, CT
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GSK Investigational Site
Decatur, Georgia 30033
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Decatur, GA
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Des Moines, Iowa 50314
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Des Moines, IA
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GSK Investigational Site
Edison, New Jersey
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Edison, NJ
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GSK Investigational Site
Elkridge, Maryland 21075
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Elkridge, MD
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GSK Investigational Site
Eugene, Oregon 97401
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Eugene, OR
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GSK Investigational Site
Fort Lauderdale, Florida 33308
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Fort Lauderdale, FL
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GSK Investigational Site
Gainesville, Florida 32610
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Gainesville, FL
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GSK Investigational Site
Grand Rapids, Michigan 49546
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Grand Rapids, MI
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Hoffman Estates, Illinois 60194
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Hoffman Estates, IL
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GSK Investigational Site
Houston, Texas 77030
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Houston, TX
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GSK Investigational Site
Kansas City, Kansas 66160
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Kansas City, KS
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GSK Investigational Site
Kirkland, Washington 98034
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Kirkland, WA
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GSK Investigational Site
La Jolla, California 92093
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La Jolla, CA
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GSK Investigational Site
LaJolla, California 92037
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LaJolla, CA
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GSK Investigational Site
Las Vegas, Nevada 89102
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Las Vegas, NV
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Los Angeles, California 90025
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Los Angeles, CA
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GSK Investigational Site
Lubbock, Texas 79410
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Lubbock, TX
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GSK Investigational Site
Madison, Wisconsin 53792
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Madison, WI
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GSK Investigational Site
Medford, Oregon 97504
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Medford, OR
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GSK Investigational Site
Miami, Florida 33136
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Miami, FL
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GSK Investigational Site
Newark, Delaware 19713
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Newark, DE
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Newport Beach, California 92663
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Newport Beach, CA
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Northbrook, Illinois 60062
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Northbrook, IL
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GSK Investigational Site
Oxnard, California 93030
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Oxnard, CA
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GSK Investigational Site
Palm Beach Gardens, Florida 33410
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Palm Beach Gardens, FL
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GSK Investigational Site
Pembroke Pines, Florida 33028
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Pembroke Pines, FL
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Philadelphia, Pennsylvania 19104
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Philadelphia, PA
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Phoenix, Arizona 85012
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Phoenix, AZ
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GSK Investigational Site
Port Charlotte, Florida 33952
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Port Charlotte, FL
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GSK Investigational Site
Raleigh, North Carolina 27614
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Raleigh, NC
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Richmond, Virginia 23298
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Richmond, VA
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GSK Investigational Site
Roanoke, Virginia 24013
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Roanoke, VA
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Rochester, New York 14642
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Rochester, NY
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San Antonio, Texas 78258
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San Antonio, TX
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GSK Investigational Site
San Jose, California 95116
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San Jose, CA
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GSK Investigational Site
Seattle, Washington 98109
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Seattle, WA
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South Weymouth, Massachusetts
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South Weymouth, MA
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Sun City, Arizona 85351
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Sun City, AZ
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Tacoma, Washington 98405
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Tacoma, WA
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Tampa, Florida 33612
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Tampa, FL
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GSK Investigational Site
Traverse City, Michigan 49684
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Traverse City, MI
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Tucson, Arizona 85724
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Tucson, AZ
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GSK Investigational Site
Walnut Creek, California 94596
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Walnut Creek, CA
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GSK Investigational Site
West Yarmouth, Massachusetts 02673
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West Yarmouth, MA
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GSK Investigational Site
Winston-Salem, North Carolina 27103
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Winston-Salem, NC
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