Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia
| Status: | Completed |
|---|---|
| Conditions: | Schizophrenia |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 10/14/2017 |
| Start Date: | August 2007 |
| End Date: | November 2008 |
A Multi-Center Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Phase IIb Proof of Concept Study With 3 Oral Groups of AZD3480 During 12 Weeks Treatment of Cognitive Deficits in Patients With Schizophrenia
The purpose of this study is to demonstrate that AZD3480 improves cognition in patients with
stable schizophrenia who are being treated with an atypical antipsychotic and who are active
cigarette smokers, to assess the safety and tolerability of AZD3480 and to define the optimal
dose(s) to be used in future trials.
stable schizophrenia who are being treated with an atypical antipsychotic and who are active
cigarette smokers, to assess the safety and tolerability of AZD3480 and to define the optimal
dose(s) to be used in future trials.
Inclusion Criteria:
- Diagnosis of schizophrenia
- Outpatient at the time of screening and randomization
- Stable housing defined as having a place to live in the community (ie, not in a
hospital or nursing home)
- Active cigarette smoking (10 or more cigarettes per day
Exclusion Criteria:
- Any significant psychiatric or neurological disease other than schizophrenia, or
current diagnosis of major depressive disorder
- Known or suspected drug or alcohol abuse within the 6 months or urine toxicology test
positive for illegal or non-prescribed substances
- Impaired vision and/or hearing making cognitive testing difficult
We found this trial at
67
sites
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials