Role of Pancreatic Triglyceride Content in Beta-cell Function
| Status: | Completed |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 21 - 99 |
| Updated: | 12/27/2017 |
| Start Date: | September 2007 |
| End Date: | August 2012 |
The study evaluates if fat accumulates in the pancreas in individuals at risk of developing
obesity-related diabetes. It also evaluates if the amount of fat in the pancreas can predict
the residual functional capacity of the pancreas (insulin secretion).
obesity-related diabetes. It also evaluates if the amount of fat in the pancreas can predict
the residual functional capacity of the pancreas (insulin secretion).
Inclusion Criteria:
- adults without prior history of pancreatic disease (other than diabetes)
Exclusion Criteria:
- use of unapproved medications
- contraindications to the MRI procedure
- contraindications to frequent blood draws
- pregnancy
- use of more than 2 alcoholic drinks/day
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