Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension

Status:	Completed
Conditions:	High Blood Pressure (Hypertension), Ocular
Therapuetic Areas:	Cardiology / Vascular Diseases, Ophthalmology
Healthy:	No
Age Range:	18 - Any
Updated:	10/14/2017
Start Date:	March 2008
End Date:	October 2008

A Randomized, Double-masked, Placebo- and Active- Controlled, Parallel-group, Multi-center, Dose-response Trial of DE-104 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

To investigate the dose-response relationship of DE-104 ophthalmic solution in lowering
intraocular pressure (IOP) in subjects with Primary Open-Angle Glaucoma or Ocular
Hypertension

Inclusion Criteria:

- Provided signed, written informed consent.

- Diagnosed with primary open-angle glaucoma or ocular hypertension.

- 18 years of age and older.

- If a subject is a female of childbearing potential, she must utilize reliable
contraceptive throughout the study, and must have a negative urine pregnancy test
prior to enrollment into this study.

Exclusion Criteria:

- Females who are pregnant, nursing or planning a pregnancy, or females of childbearing
potential who are not using a reliable method of contraception.

- Presence of any abnormality or significant illness that could be expected to interfere
with the study.

We found this trial at

sites

Associated Glaucoma Consultants

840 Walnut Street
Philadelphia, Pennsylvania 19107

from

Philadelphia, PA