Using Beta Blockers to Treat Mitral Regurgitation
| Status: | Terminated |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology, Cardiology, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 8/16/2018 |
| Start Date: | October 2007 |
| End Date: | September 2009 |
Beta-Blockade in Chronic Mitral Regurgitation: Moving From the Laboratory Experiment to Clinical Investigation
The purpose of this study tests whether beta-blocker will benefit asymptomatic patients with
chronic primary mitral regurgitation.
chronic primary mitral regurgitation.
The purpose of this study tests 1) whether Toprol xl, a beta-blocker will benefit
asymptomatic patients with chronic primary mitral regurgitation; 2) investigate the effects
of chronic mitral regurgitation on left ventricular remodeling, left ventricular
function,exercise capacity and clinical symptoms.
asymptomatic patients with chronic primary mitral regurgitation; 2) investigate the effects
of chronic mitral regurgitation on left ventricular remodeling, left ventricular
function,exercise capacity and clinical symptoms.
Inclusion Criteria:
- Diagnosis of sever primary mitral regurgitation
- Normal subjects
Exclusion Criteria:
- Left ventricle ejection fraction of <55% pre and post operation
- Pregnancy or Lactation
- Secondary mitral regurgitation due to coronary artery disease, cardiomyopathy,
uncontrolled hypertension, or severe aortic stenosis.
We found this trial at
1
site
1 Medical Center Blvd
Winston-Salem, North Carolina 27103
Winston-Salem, North Carolina 27103
(336) 716-2011
Wake Forest University Baptist Medical Center Welcome to Wake Forest Baptist Medical Center, a fully...
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