The AIM Study: Assessing the Impact of Margin Reduction

Status:	Completed
Conditions:	Prostate Cancer, Cancer
Therapuetic Areas:	Oncology
Healthy:	No
Age Range:	18 - Any
Updated:	10/14/2017
Start Date:	July 2008
End Date:	September 2009

This study will observe patients who receive external beam radiation for prostate cancer.
These patients will be localized and tracked (targeted) with the Calypso 4D Localization
System. These patients will have a uniform treatment plan with reduced PTVs (prostate
treatment volume) and will be assessed at multiple time points for quality of life and side
effects related to radiation therapy.

EPIC surveys and adverse events recorded and categorized using the CTCAE v3.0 will be
collected and summary statistics performed. The patient's individual tracking graphs will be
evaluated for motion type and frequency.

Inclusion Criteria:

1. Patients who are planning to receive external beam radiation of prostate

2. Patients who are to be implanted with Beacon Transponders in the prostate

3. 18 years of age or older.

4. Histologically confirmed diagnosis of prostate cancer.

5. Ability to comply with study visit schedule.

6. Signed informed consent form.

Exclusion Criteria:

1. Any patients who have received other investigational therapy within the last 60 days
are excluded.

2. Individuals that have previously been implanted with permanent Beacon transponders are
excluded.

3. Patients that have any prosthetic implants in the pelvic region that contain metal or
conductive materials (e.g., an artificial hip).

4. Any other medical or other condition that would, at the discretion of the
investigator, preclude the individual from participation in a clinical study.

We found this trial at

sites

21st Century Oncology-Scottsdale

Scottsdale, Arizona 85251

from

Scottsdale, AZ