The Role of Endothelin in Pulmonary Hypertension
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension), High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 11/29/2018 |
| Start Date: | February 1999 |
| End Date: | June 2011 |
The purpose of the study is is to determine the effect, on the lung circulation, of BQ-123,
an investigational compound which is not approved by the FDA.
an investigational compound which is not approved by the FDA.
Endothelin levels are increased in patients with pulmonary hypertension. We wish to compare
the effect of an endothelin antagonist on pulmonary hypertension due to a variety of causes.
the effect of an endothelin antagonist on pulmonary hypertension due to a variety of causes.
Inclusion Criteria:
- Healthy volunteers or known diagnosis of pulmonary hypertension
Exclusion Criteria:
- hypertension due to other reasons (not pulmonary)
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