A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model

Inclusion Criteria include, but are not limited to:

- Have a reported history of dry eye in both eyes;

- Have a history of use of or desire to use an eye drop for dry eye symptoms within the
past 6 months.

Exclusion Criteria include, but are not limited to:

- Have contraindications to the use of the study medications;

- Have known allergy or sensitivity to the use of the study medications or diagnostic
dyes;