Effects of Naturally Silicon-Rich Water on Bone Metabolism in Women
| Status: | Completed |
|---|---|
| Conditions: | Orthopedic, Endocrine, Gastrointestinal |
| Therapuetic Areas: | Endocrinology, Gastroenterology, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 10/14/2017 |
| Start Date: | June 2007 |
| End Date: | February 2011 |
Effects of Naturally Occurring Silicon in Drinking Water on Bone Metabolism
The aim of this research study is to determine by laboratory analyses the effects of drinking
silicon-rich water on bone health. This will be determined from blood and urine samples from
subjects who will be asked to drink 1 liter per day of either silicon-rich water or water
without silicon for 12 weeks.
silicon-rich water on bone health. This will be determined from blood and urine samples from
subjects who will be asked to drink 1 liter per day of either silicon-rich water or water
without silicon for 12 weeks.
Inclusion Criteria:
- Body mass index (BMI) < 30
- Postmenopausal women with no evidence of osteoporosis by dual energy X-ray
absorptiometry (DEXA) scan (T ≥ -2 in the total hip and lumbar spine).
- Pre- or peri-menopausal women with osteopenia but no evidence of osteoporosis by DEXA
scan (−1.5 ≤ T ≤ −2 in the total hip and lumbar spine)
- No estrogens or corticosteroids
- No prior history of bisphosphonate medication
- Otherwise in good health with no significant illnesses which could affect bone
metabolism such as hypercortisolism, untreated hypothyroidism, treatment with statins
or other drugs affecting bone metabolism other than calcium and vitamin D3.
- No change in exercise regimen or calcium intake in the past 3 months.
- Subject must sign the Institutional Review Board-approved written informed consent
prior to the initiation of any study specific procedures or randomization. A subject
will be excluded for any condition that might compromise the ability to give truly
informed consent for participation in the study.
Exclusion Criteria:
- Males
- Premenopausal women with DEXA T scores ≥ -1.5 or ≤ -2.
- Postmenopausal women with DEXA T scores ≤ -2.
We found this trial at
1
site
University of California at Los Angeles The University of California, Los Angeles (UCLA) is an...
Click here to add this to my saved trials
