Gabapentin vs Chlordiazepoxide for Ambulatory Alcohol Withdrawal
Status: | Completed |
---|---|
Conditions: | Psychiatric |
Therapuetic Areas: | Psychiatry / Psychology |
Healthy: | No |
Age Range: | 18 - 80 |
Updated: | 10/14/2017 |
Start Date: | March 2004 |
End Date: | September 2010 |
Comparison of Chlordiazepoxide and Gabapentin for Outpatient Alcohol Detoxification Treatment
A randomized, double-blind controlled trial comparing treatment outcomes between
chloriazepide, or gabapentin to treat alcohol withdrawal syndrome in alcohol dependent
veteran subjects. The objective of this trial is to compare the safety and effectiveness of
these two medications. Intervention is a fixed dose taper of chlordiazepoxide, or gabapentin
over 6 days. Subjects will be evaluated for 7-10 days to monitor alcohol abstinence,
withdrawal severity scores, adverse events including ataxia, sedation, cognitive function and
alcohol craving.
chloriazepide, or gabapentin to treat alcohol withdrawal syndrome in alcohol dependent
veteran subjects. The objective of this trial is to compare the safety and effectiveness of
these two medications. Intervention is a fixed dose taper of chlordiazepoxide, or gabapentin
over 6 days. Subjects will be evaluated for 7-10 days to monitor alcohol abstinence,
withdrawal severity scores, adverse events including ataxia, sedation, cognitive function and
alcohol craving.
Inclusion Criteria:
- Alcohol dependent at risk for withdrawal symptoms
Exclusion Criteria:
- Benzodiazepine dependent
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