Diagnosis and Management of Inflammatory and Infectious Diseases

This protocol is being established to cover the evaluation of patients with inflammatory
and/or infectious diseases which are not covered under previously existing protocols. The
purpose of such a protocol is that frequently patients are referred to us with either
diagnosed or undiagnosed illnesses which would be of interest to our teaching program or
which would serve as a source of patients to subsequently be entered into established,
ongoing protocols studies. Such patients are admitted to the protocol and handled according
to accepted medical practice of diagnosis and treatment.

- INCLUSION CRITERIA:

1. Known or suspected exposure to infection, as determined by the Principal
Investigator OR presence of signs and symptoms of an infectious or inflammatory
disease.

2. Age range: 3 years of age and older.

3. NIAID/LIR investigator who has an interest in the patient's illness and is
willing to serve as attending physician to supervise the patient s medical care
at NIH.

4. Primary physician outside the NIH.

5. Willingness to have samples stored, but this is not a condition for enrollment.

EXCLUSION CRITERIA:

1. Inability to sign informed consent or lack of designated Health Power of Attorney.