Effects of Black Tea Intake on Serum Lipids
| Status: | Completed |
|---|---|
| Conditions: | High Cholesterol |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 45 - 65 |
| Updated: | 12/15/2017 |
| Start Date: | April 2002 |
Effects of Black Tea Intake on Serum Lipids in Mildly Hypercholesterolemic Adults A Randomized Diet-controlled Crossover Trial
A diet-controlled clinical trial which attempts to provide estimates of the effect of black
tea consumption on serum lipids under tightly controlled conditions, including a controlled
diet. Mildly hypercholesterolemic individuals (total cholesterol levels between 4.9 and 6.7
mmol/L, 190 and 260 mg/dl), non-smoking, chronic disease-free individuals were enrolled in a
15-week, double blind, randomized crossover trial, during which they consumed a controlled
low-flavonoid diet plus 5 cups of black tea or a tea-like placebo over two 4-week treatment
periods.
tea consumption on serum lipids under tightly controlled conditions, including a controlled
diet. Mildly hypercholesterolemic individuals (total cholesterol levels between 4.9 and 6.7
mmol/L, 190 and 260 mg/dl), non-smoking, chronic disease-free individuals were enrolled in a
15-week, double blind, randomized crossover trial, during which they consumed a controlled
low-flavonoid diet plus 5 cups of black tea or a tea-like placebo over two 4-week treatment
periods.
Inclusion Criteria:
- between 45-65 years old
- mildly hypercholesterolemic (total cholesterol levels between 4.9 and 6.7 mmol/L, 190
and 260 mg/dl)
- high-density lipoprotein cholesterol (HDL-C) between 0.9 and 1.6 mmol/L (35 and 65
mg/dl)
- triglyceride (TG) concentrations below 6.8 mmol/L (600 mg/dl)
- habitually consumed a typical American diet with low dietary flavonoid intake (<4
one-half cup servings of fruits and vegetables/day) and low intake (<1 serving/day) of
soy-rich foods, nuts, herbs, and spices (besides salt and pepper)
- aspartate aminotransferase (AST) between 0 and 55 mg/L
- creatinine between 70.7 and 150.3 mmol/L (0.8 and 1.7 mg/dl)
- glucose between 3.3 and 6.4 mmol/L (60 and 115 mg/dl)
Exclusion Criteria:
- current smoker
- usage of high amounts of antioxidant vitamin supplements (>3 times the Recommended
Dietary Allowance (RDA) of vitamins E, C, and selenium, or >10 mg/day of beta
carotene)
- had been diagnosed with diabetes, coagulation disorders, chronic pulmonary disease,
current active malignancy, renal disease requiring dialysis, malabsorption, or
gastrointestinal disorders, or had a history of cardiovascular disease.
- antihypertensive, immunosuppressive, cholesterol lowering, or anticoagulant
medications
- consuming >3 servings of alcohol daily
- Pre-menopausal (women)
We found this trial at
1
site
1100 South Washington Avenue
Minneapolis, Minnesota 55454
Minneapolis, Minnesota 55454
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