Effects of Resistant Starch in a Beverage on Post-prandial Glycemic and Insulinemic Responses

- About two-thirds of adults in the United States are overweight or obese which can cause
adverse health consequences for those individuals. Post-prandial hyperglycemia is one of
these possible consequences and is associated with a higher risk for Type 2 Diabetes.
Controlling hyperglycemia is important in the prevention of the onset of diabetes and
obesity. Resistant starch is a dietary carbohydrate which is not completely digested in
the gut and produces energy for the body to use. The investigators are interested in
assessing the effects of resistant starch on postprandial blood glucose and insulin
concentrations.

- Aim: To assess the effects of a resistant starch on post-prandial blood glucose and
insulin concentrations.

- Hypothesis: A beverage with a resistant starch will blunt and sustain the post-prandial
rise in blood glucose and insulin concentrations compared to a beverage with
maltodextrin (an easily digested carbohydrate).

Inclusion Criteria:

- Thirty healthy men and women (aged 18-29y) will be recruited from the greater
Lafayette, IN region with the expectation that ≥20 subjects will complete the study.
Subjects must weigh >110 pounds, with a BMI between 20.0 and 29.9.

Exclusion Criteria:

- Weight change > 3kg in the past 3 months

- Exercising vigorously over the past 3 months as well as no exercise 3 days prior to
testing day

- Intestinal disorders including lipid mal-absorption or lactose intolerance

- Abnormal liver or kidney function tests; fasting blood glucose >100mg/dL

- Smoking

- Drinking more than 2 alcoholic drinks per day

- Taking lipid-lowering medications or dietary supplements affecting plasma cholesterol
concentration.

- Subjects must not be pregnant or lactating.