Delayed 18F-FDG PET/CT in Improving Visualization of Brain Tumors in Patients With Glioblastoma
| Status: | Withdrawn |
|---|---|
| Conditions: | Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - 99 |
| Updated: | 3/2/2019 |
| Start Date: | June 8, 2016 |
| End Date: | December 12, 2018 |
Improved Visualization of Glioblastoma Using Delayed 18F-FDG PET/CT.
This clinical trial studies how well delayed fludeoxyglucose F-18 (18F-FDG) positron emission
tomography (PET)/computed tomography (CT) works in improving visualization of brain tumors in
patients with glioblastoma. Radiotracers such as 18F-FDG are highly taken up by tumors in the
brain and are visualized using PET/CT. Increasing the interval of time between 18F-FDG
administration and PET/CT scan may improve the visualization of brain tumors in patients with
glioblastoma.
tomography (PET)/computed tomography (CT) works in improving visualization of brain tumors in
patients with glioblastoma. Radiotracers such as 18F-FDG are highly taken up by tumors in the
brain and are visualized using PET/CT. Increasing the interval of time between 18F-FDG
administration and PET/CT scan may improve the visualization of brain tumors in patients with
glioblastoma.
PRIMARY OBJECTIVES:
I. To improve the visualization/delineation of glioblastoma lesions using delayed 18F-FDG
PET/CT imaging.
OUTLINE:
Patients receive fludeoxyglucose F-18 intravenously (IV). Patients then undergo a standard of
care PET/CT scan at 60 minutes and a second PET/CT scan at 240 minutes after injection.
Note:
Standard Uptake Value (SUV) is defined for state-of-the art PET/CT scanners as Standardized
uptake values = count activity per ml within region of interest (MBq/ml)/[injected dose
(MBq)/body weight (kgx1000)]
I. To improve the visualization/delineation of glioblastoma lesions using delayed 18F-FDG
PET/CT imaging.
OUTLINE:
Patients receive fludeoxyglucose F-18 intravenously (IV). Patients then undergo a standard of
care PET/CT scan at 60 minutes and a second PET/CT scan at 240 minutes after injection.
Note:
Standard Uptake Value (SUV) is defined for state-of-the art PET/CT scanners as Standardized
uptake values = count activity per ml within region of interest (MBq/ml)/[injected dose
(MBq)/body weight (kgx1000)]
Inclusion Criteria:
- Patients with histologically proven high grade glioma scheduled for 18F-FDG PET/CT
Exclusion Criteria:
- Severe psychiatric illness
- Inability to give written consent
- Breast feeding/pregnancy
We found this trial at
1
site
Los Angeles, California 90095
Principal Investigator: Johannes Czernin
Phone: 310-794-1005
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